Q74ZJ5
Gene name |
SEN54 (AGR205C) |
Protein name |
tRNA-splicing endonuclease subunit SEN54 |
Names |
tRNA-intron endonuclease SEN54 |
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AGR205C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q74ZJ5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q74ZJ5-F1 | Predicted | AlphaFoldDB |
No variants for Q74ZJ5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q74ZJ5 | |||||
No associated diseases with Q74ZJ5
1 regional properties for Q74ZJ5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | tRNA-splicing endonuclease, subunit Sen54, N-terminal | 73 - 138 | IPR024336 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| tRNA-intron endonuclease complex | A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA-intron endonuclease activity | Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA-type intron splice site recognition and cleavage | RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTEAEELSVA | LGLHDSDAEE | DALAQDWSEM | AKLVKKANQH | ALPRRGEKDY | EPDGTDAQAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLHTAKETMF | GTLLNSVRGS | TVKTLIKAYW | EEEQRMARIP | NARGSFTNTM | GKVDKHGQCW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LQLHEFVYLV | ERGTVSPYLA | LTVGDEKSNH | EDVLLSVQDV | YALFSSTEEL | DEFLVYAHLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RLGFIVVSTD | NPPAHVTSFY | PPLSQKSSAS | SNWFCHIHSW | LKTPQNLFHV | PLYHPLHFLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HRYTSSPQLY | EELSQHIPFK | KVPHDINELR | EERNNGILNP | NVKQWKIAFN | VWKPKSSFKK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KTPGLPDFQV | VVYNKDNAGQ | QFPTYDEFRS | IFHRLDYRFD | FLNELDVDDS | AWDDYTYTDG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MPTREFMQRN | KIAPSQPHSG | GDSRKKKART | YPQHIAQIRR | LKSGFKSFIL | SVIDDGLVSF |
| 430 | 440 | 450 | |||
| VRIAESDFGS | SNIWYTPPSQ | TGTTNNRTRS | DKVDV |