Q74ZF6

PR
Gene name
MET3
Protein name
Sulfate adenylyltransferase
Names
ATP-sulfurylase, Sulfate adenylate transferase, SAT
Species
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
KEGG Pathway
ago:AGOS_AGR322W
EC number
2.7.7.4: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q74ZF6

Entry ID Method Resolution Chain Position Source
AF-Q74ZF6-F1 Predicted AlphaFoldDB

No variants for Q74ZF6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q74ZF6

No associated diseases with Q74ZF6

11 regional properties for Q74ZF6

Type Name Position InterPro Accession
domain Protein kinase domain 1079 - 1346 IPR000719
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 1080 - 1337 IPR001245
domain Sema domain 27 - 516 IPR001627
domain IPT domain 563 - 656 IPR002909-1
domain IPT domain 657 - 740 IPR002909-2
domain IPT domain 742 - 837 IPR002909-3
domain IPT domain 839 - 935 IPR002909-4
active_site Tyrosine-protein kinase, active site 1201 - 1213 IPR008266
domain PSI domain 520 - 563 IPR016201
binding_site Protein kinase, ATP binding site 1085 - 1111 IPR017441
domain Tyrosine-protein kinase, catalytic domain 1079 - 1338 IPR020635

Functions

Description
EC Number 2.7.7.4 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
sulfate adenylyltransferase (ATP) activity Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.

5 GO annotations of biological process

Name Definition
cysteine biosynthetic process The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
hydrogen sulfide biosynthetic process The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
methionine biosynthetic process The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
sulfate assimilation via adenylyl sulfate reduction The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase.
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSPHGGILQ DLVARDAEKK DRLLHEAQGL PQWNLTARQL CDIELILNGG FSPLTGFLGK
70 80 90 100 110 120
EDYESVVQNS RLTSGLLWTI PITLDVDEEF AKSVNLGERI ALLQDDDIFV AIITVSDIYT
130 140 150 160 170 180
PDKKVEADKV FRGDEEHPAI QYLNETAGDI YLGGELEAIQ LPAHYDYLNL RKSPAALRAD
190 200 210 220 230 240
FATQQWDRVV AFQTRNPMHR AHRELTIRAA KEHNAKVLLH PVVGLTKPGD IDYHTRIKVY
250 260 270 280 290 300
KEIVKRYPEG IAQLALLPLA MRMAGDREAV WHAIIRKNYG ATHFIVGRDH AGPGTNSKGD
310 320 330 340 350 360
DFYGPYDAQV LVESYKNELG IEVVPFKLIT YLPDKDIYLP VDEIDGSVKT LTISGTELRK
370 380 390 400 410 420
RLREGTDIPD WFTYPEIVEI LRQYNPPRYR QGFVIVVNHE NPKRIANALL STFLQVGGGR
430 440 450 460 470 480
QYKIFDHQGQ PQLLELIPDF VKSGTGLIVT SPLPSSVDAH NIYELNTYPS AHIKVSATEP
490
VTEIVQKTVF FLEDNKFFQF