Q74L37

PR
Gene name
secA2
Protein name
Protein translocase subunit SecA 2
Names
Species
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
KEGG Pathway
ljo:LJ_0388
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

496-593 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q74L37

Entry ID Method Resolution Chain Position Source
AF-Q74L37-F1 Predicted AlphaFoldDB

No variants for Q74L37

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q74L37

No associated diseases with Q74L37

8 regional properties for Q74L37

Type Name Position InterPro Accession
domain Helicase, C-terminal 410 - 575 IPR001650
domain SecA DEAD-like, N-terminal 2 - 381 IPR011115
domain SecA Wing/Scaffold 586 - 771 IPR011116
domain SecA, preprotein cross-linking domain 225 - 337 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 79 - 246 IPR014001
domain SecA motor DEAD 1 - 568 IPR014018
conserved_site SecA conserved site 479 - 494 IPR020937
domain SecA, C-terminal helicase domain 399 - 538 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLTDRLRLKK ARKLLNKINK LGPKMQAMSD EKLQGQTAIF KKQLKEGKSL DDILPEAYAT
70 80 90 100 110 120
VREADKRILG MFPYDVQVLG AIVLHNGSIA EMKTGEGKTL VATMALYLNA LEGKGAMLVT
130 140 150 160 170 180
PNGYLASRDK KELAPVYEWL GLSVSLAFAE EKDSKKKITA KTKRKWYNSD IVYTTASSLA
190 200 210 220 230 240
FDYLFNNLAS SKENQYLRPF NYVIVDEVDE VLLDEAQTPF VVSSSPNVQS NLYHLADQFV
250 260 270 280 290 300
RLLDPEVDYV FKKDDQLFWL TAHGIEKAEQ FFKLDSLFSN ESRSVYRHII LAMGAHLTMR
310 320 330 340 350 360
RGHDYLVVKG EVVLLDEDSG RLKRGVQVST GIHQAVEAKE KVELTKIQKT AASITFPALF
370 380 390 400 410 420
ALFNKVSGMS GTAKVNEEEF LQTYNLKVVT IPTRVPVIRK DYRPLIFLTT IDKLMTAVDD
430 440 450 460 470 480
VVEMHKTGRP VLLVAGSVEN SEIISELLLN IGIPHNVLNA YNAAYEAQII KNAGQKNAVT
490 500 510 520 530 540
IATNMAGRGT DIKLGPGVKE LGGLAVIGTE MLPKRVELQL AGRAGRQGDP GSSQFLISLE
550 560 570 580 590 600
DSFISSNNTP RQKKYYRKLM KKKSKGKDIT LLSGPRIRFS LLMLRTRKED LNELMRSQTN
610 620 630 640 650 660
KMEIILSLQR KNFYTRRDKI MKTDDLQEDV DRIIDNALNL YLEKQDLSNK SDLKYFINQH
670 680 690 700 710 720
VTYQQVNVPD NLKTKKAIKD FLKELAYKIL DEKKHVLINK KQANDFYQQV IISSMDGNWI
730 740 750 760 770 780
DQVDRIEKIK INAQQWGRSG RPQDLLHQEK AFEAYKDFLD KITLSTFDNL LLSKIFTNEK
GQLVVVFN