Q74GT9

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
KEGG Pathway
gsu:GSU0156
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q74GT9

Entry ID Method Resolution Chain Position Source
AF-Q74GT9-F1 Predicted AlphaFoldDB

No variants for Q74GT9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q74GT9

No associated diseases with Q74GT9

3 regional properties for Q74GT9

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 278 - 287 IPR020557
domain Fumarate lyase, N-terminal 9 - 303 IPR022761
domain Argininosuccinate lyase, C-terminal 366 - 434 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAHEKLWGGR FSEPTDQFVE EFTASIDFDK RLYHQDIRGS IAHARMLGKQ GILPMAEVEK
70 80 90 100 110 120
IVAGLQEVLA RIEAGKFDFS VALEDIHMNI EARLTEKIGE AGKRLHTGRS RNDQVALDIR
130 140 150 160 170 180
LYLRDEIVEI SAYLDMLVDS LIYQAEANLG VIMPGYTHLQ TAQPILFSHH MMAYVEMFTR
190 200 210 220 230 240
DKGRMEDCLR RMNVLPLGAG ALAGTTFPID REHVAELLDF PGVTRNSLDS VSDRDFALEF
250 260 270 280 290 300
MGASSILMMH LSRFSEELIL WSTSEFKFVE LTDSFCTGSS IMPQKKNPDV PELVRGKTGR
310 320 330 340 350 360
VYGNLMALLT VMKALPLAYN KDMQEDKEPL FDTIDTVKGS LKIFADMVRE MRINAGNMRA
370 380 390 400 410 420
AAAKGFSTAT DVADYLVRQG MPFRDAHEVV GKTVAYCIAN GKDLPDLTMD EWQGFSDKIG
430 440 450
EDIFDAITLE ASVNARVATG GTALERVKAE IERAKVGR