Q74FF1

PR
Gene name
clpB (GSU0658)
Protein name
Chaperone protein ClpB
Names
Species
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
KEGG Pathway
gsu:GSU0658
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

115-188 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q74FF1

Entry ID Method Resolution Chain Position Source
AF-Q74FF1-F1 Predicted AlphaFoldDB

No variants for Q74FF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q74FF1

No associated diseases with Q74FF1

9 regional properties for Q74FF1

Type Name Position InterPro Accession
domain AAA+ ATPase domain 200 - 345 IPR003593-1
domain AAA+ ATPase domain 595 - 743 IPR003593-2
domain ATPase, AAA-type, core 205 - 338 IPR003959-1
domain ATPase, AAA-type, core 594 - 759 IPR003959-2
domain Clp, repeat (R) domain 2 - 148 IPR004176
conserved_site ClpA/B, conserved site 1 296 - 308 IPR018368
domain Clp ATPase, C-terminal 766 - 857 IPR019489
conserved_site ClpA/B, conserved site 2 629 - 647 IPR028299
domain ClpA/ClpB, AAA lid domain 346 - 436 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
cellular response to heat Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIRPEKMTIK TQEALAGAQQ LAARQGNGSI EPEHLLVSLL EQEGGLIAPI IQKVGGAPAA
70 80 90 100 110 120
LRSAADVLVK RLPQVSGATA QAYLSPALNR ILDAAQREAD TMKDEFVSTE HLLLGFFADR
130 140 150 160 170 180
QCAAARALLD AGVSRDNVLA ALMEIRGGER VTDQNPEDTY QALAKYARDL TDLARQGKLD
190 200 210 220 230 240
PVIGRDDEIR RVLQVLSRRT KNNPVLIGEP GVGKTAIVEG LAQRIVSGDV PETLKDKRLV
250 260 270 280 290 300
ALDMGALIAG AKYRGEFEER LKAVIREVAK SEGKVILFID ELHTLVGAGA AEGAMDASNM
310 320 330 340 350 360
LKPALARGEL HCIGATTLNE YRKYIEKDAA LERRFQQVYT GEPSVEDTIA ILRGLKEKYE
370 380 390 400 410 420
NYHGIRIKDS AIIAAATLSD RYITDRFLPD KAIDLIDEAA SRLRIEIDSM PTEIDEVERR
430 440 450 460 470 480
IIQLEIEKQA LLRESQDPHS LERLKKLADE LEELKAKSAE LKGHWQREKD IIGRVSSLRQ
490 500 510 520 530 540
RLEEKREEAK KAEREGNLAR TAEIRYGEIP AIEKEIADRS AELEDIRKEG KMLPEEVDGE
550 560 570 580 590 600
LVAEIVSRWT GIPVSRMMEG EADKLVHMED RLITRVVGQD EALVLVANAI RRARSGLSDP
610 620 630 640 650 660
NRPIGSFLFL GPTGVGKTET AKALAEFLFN DDQAIVRIDM SEYQEKHTVA RLIGAPPGYV
670 680 690 700 710 720
GYEEGGQLTE AVRRRPYSIV LFDEIEKAHP EVFNVLLQVL DDGRLTDGQG RTVDFRNTVI
730 740 750 760 770 780
IMTSNLGSQW IQQYGSSDYA RMKAMVTETL KEGFKPEFLN RIDEIVIYHA LPLEQIKKIV
790 800 810 820 830 840
DIQVECLKQR LADRRIVLEL SDKAREYLSR EGYDPAYGAR PLKRTIQRKI QDPLALALLE
850 860
GKFQEGDTVR VDLSVSGEEL VITKK