Q73NP8
Gene name |
truB |
Protein name |
tRNA pseudouridine synthase B |
Names |
tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase |
Species |
Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104) |
KEGG Pathway |
tde:TDE_1104 |
EC number |
5.4.99.25: Transferring other groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q73NP8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q73NP8-F1 | Predicted | AlphaFoldDB |
No variants for Q73NP8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q73NP8 | |||||
No associated diseases with Q73NP8
1 regional properties for Q73NP8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Pseudouridine synthase II, N-terminal | 27 - 193 | IPR002501 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.99.25 | Transferring other groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| tRNA pseudouridine synthase activity | Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA pseudouridine synthesis | The intramolecular conversion of uridine to pseudouridine in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELNKNLIIP | FAKQAGLTSF | ASMSAVKKAL | STKKVGHTGT | LDLFADGLLV | LLTGQLTRLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DIISAEKKTY | EAWVEFGTET | DTLDPEGEPV | LTAPLPSYKN | LTESIPSFLG | KILQRPPEFS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIKINGKRAS | DRIRSGEKIK | IAEREIEIFK | IELKGIITDS | GLEFTEKDFT | NINAELKIRY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AHIVVECSKG | TYIRSLVRDL | ARKASSCAYV | RALRRTAVGN | FKLEDAAGFD | LLNNFSAAPE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NLFLKEKKIL | DAAAGKKFYK | QKEIDFLEIM | AKSIIFSPKT | AENLKLPYLF | LDRKYLNDFY |
| 310 | 320 | 330 | 340 | 350 | |
| NGKKIKFNWF | LNTDEVLENI | TGLDLENKKT | CVFCGDLWIG | IIGLNKNCPK | YETVIKN |