Q73NP6

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
KEGG Pathway
tde:TDE_1106
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-308 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q73NP6

Entry ID Method Resolution Chain Position Source
AF-Q73NP6-F1 Predicted AlphaFoldDB

No variants for Q73NP6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q73NP6

No associated diseases with Q73NP6

5 regional properties for Q73NP6

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 375 - 544 IPR000795
domain Small GTP-binding protein domain 378 - 534 IPR005225
domain Translation initiation factor IF-2, N-terminal 300 - 350 IPR006847
domain Translation initiation factor IF- 2, domain 3 652 - 766 IPR023115
domain Translation initiation factor IF-2, domain II 551 - 645 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIENTNKPD VILNKKSSKA ADSKPESGKT DSKRKVVVKV SKTSAGKSKK PESSSEESSG
70 80 90 100 110 120
GKASGKQVIS VKKASSQSSK PAEASVKEKK PDERLEETKK TAPRFEDKKS DAPSAQNEKR
130 140 150 160 170 180
SFDSAKKEEK QTERKKPTPS SIDSIDFASK RPNVKAGNLA DSGRRNNRGQ GNRPQRPGGQ
190 200 210 220 230 240
GQGQPGQGRR RESNFSGAQA RAYSDGKKQG FRTGQGGQQG RPGDRPQNRP GFGGPRPGAA
250 260 270 280 290 300
PAPIPVEKNK AQTNKKAHKA KKEIYNKKNK EEEFFEERLL NQKKKQKEKI HNIPKQIEIM
310 320 330 340 350 360
ESISVSELAK KMNLKASELI GKLMGMGMMV TMNQSIDADT ATILASEYDC DVKIVSLYDE
370 380 390 400 410 420
TVIESKEDDL SELQPRPPVV TIMGHVDHGK TKTLDAIRSS NVIAGEFGGI TQHIGAYTVN
430 440 450 460 470 480
THGGKITFLD TPGHEAFTMM RARGAEITDI VVLVVAADDG VMPQTIEAIN HARDAKVPII
490 500 510 520 530 540
VAVNKVDKPE ANVDKVKTRL SELGLMPEEW GGDTMFVEIS ALKKLGLDNL LDTILLQAEV
550 560 570 580 590 600
LELKANYTCN AEGKVIESRI DHGRGVVATI IVQRGTLRTG DPYVAGIYSG RVRAIFNDRG
610 620 630 640 650 660
EKIDEATPSM PVEILGLEGM PNAGDPFQVT DSERIARQIS DKRQELKRFE DSRNVKKVTL
670 680 690 700 710 720
DNLYETIHDG EILELKVIIK GDVQGSVEAL KQSLEKLSTP EIRLNVIHAS AGAINDSDVM
730 740 750 760 770 780
LAAADSNALI IGFNVRPTPQ AKLLADQEKV DIRKYTVIYK AVEEIQLAME GMLSPDIKEQ
790 800 810 820 830 840
VIGMVEVRNT FKVPKIGKIA GCYVLEGVVK RNCAVHVIRD GIVVHSGKLS SLKRFKDDAK
850 860 870 880 890
EVAAGFECGI GIEDFNDIQV DDQLEIIEMI QVARKLSDSE KYKAPEIKEE GTETDE