Q73LG6

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
KEGG Pathway
tde:TDE_1898
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

820-922 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q73LG6

Entry ID Method Resolution Chain Position Source
AF-Q73LG6-F1 Predicted AlphaFoldDB

No variants for Q73LG6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q73LG6

No associated diseases with Q73LG6

9 regional properties for Q73LG6

Type Name Position InterPro Accession
domain Helicase, C-terminal 441 - 648 IPR001650
conserved_site SEC-C motif 902 - 920 IPR004027
domain SecA DEAD-like, N-terminal 6 - 409 IPR011115
domain SecA Wing/Scaffold 630 - 842 IPR011116
domain SecA, preprotein cross-linking domain 228 - 365 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 632 IPR014018
conserved_site SecA conserved site 507 - 522 IPR020937
domain SecA, C-terminal helicase domain 427 - 602 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLDSIIKILF GSKHERDIKA MLPILHKINE KEAWALSLSE EEFKAKTDEF RERYQKGESL
70 80 90 100 110 120
DSFIPEAFAL AREAARRILG ERPYDVQILG SLVLHSGKIV EMKTGEGKTL MSVAAAYLNS
130 140 150 160 170 180
LTGKGVHIVT VNDYLAERDA DWMRPVYSYL GVSVGVILSN MENDARRIEY NCDITYGTNN
190 200 210 220 230 240
EFGFDYLRDN MQMRLKDKTQ REFSFAIVDE IDSILIDEAR TPLIISGAAE DDTQRFFEVD
250 260 270 280 290 300
RLIGQLKEVE KNPETGEYPN ELEGEEVIGD YTIDEKSKRV SFTDSGMLHI QDILQRQGLI
310 320 330 340 350 360
KSGNLFDEEN FEYIHYFTQS VRAHVLFHID VDYVIQDGQV QIVDEFTGRV LEGRRYSDGL
370 380 390 400 410 420
HQAIEAKEHI KIAQRNRTLA TITFQNFFRM YDKLSGMTGT ADTEAVEFTK IYNLDVVVIP
430 440 450 460 470 480
TNLPVARKDE HDVIYLNEND KFEALCTEIS EAYKRGQPVL VGTVSIEKSE LISKLLTKRG
490 500 510 520 530 540
VRHEVLNAKN HEREALIIAE AGAKGSVTIA TNMAGRGTDI KLGGSPEMRA KKRTGTNPNP
550 560 570 580 590 600
DYYEKVLAEE YAKWQSDYNE VKELGGLYVI GTERHESRRI DNQLRGRSGR QGDPGRSKFF
610 620 630 640 650 660
LSLDDDLMRL FGGENLKNVM SKIGMRAGEP IEHPWINKSI EKAQTKVENR NFDIRKHLLE
670 680 690 700 710 720
YDDVLNEQRS FIYEQRNAIL EDENLIERIY ATLEEFISEK FDEYSSSSKA EKEERARLIK
730 740 750 760 770 780
DIFREKFSYT LTEEDFANID KKNHEEEINE FVEHFTKELK EKEALAGKEN LNMFIRYQYL
790 800 810 820 830 840
QAIDKKWLDH LENLESLREA VYLRSYGQKN PLTEYKLEGF DIFYSMLDDI RIEIASRLVR
850 860 870 880 890 900
VQISTEEEAH ASRQMRSIQG NAQHNSMGSF SGSGHGMGPT ALSARSRPEN AQVVRTVPKV
910 920
GRNDPCPCGS GKKYKYCCGK NG