Q73K92

PR
Gene name
clpB (TDE_2327)
Protein name
Chaperone protein ClpB
Names
Species
Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)
KEGG Pathway
tde:TDE_2327
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

107-187 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q73K92

Entry ID Method Resolution Chain Position Source
AF-Q73K92-F1 Predicted AlphaFoldDB

No variants for Q73K92

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q73K92

No associated diseases with Q73K92

9 regional properties for Q73K92

Type Name Position InterPro Accession
domain AAA+ ATPase domain 197 - 343 IPR003593-1
domain AAA+ ATPase domain 603 - 768 IPR003593-2
domain ATPase, AAA-type, core 202 - 334 IPR003959-1
domain ATPase, AAA-type, core 602 - 765 IPR003959-2
domain Clp, repeat (R) domain 3 - 145 IPR004176
conserved_site ClpA/B, conserved site 1 293 - 305 IPR018368
domain Clp ATPase, C-terminal 771 - 860 IPR019489
conserved_site ClpA/B, conserved site 2 637 - 655 IPR028299
domain ClpA/ClpB, AAA lid domain 342 - 441 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNIDKYTVKA SEAVQEASSL AQRDDHSQVE SEHLLYVLLE QEDGIVPPLV EKIGVSPESL
70 80 90 100 110 120
LDDLDKMLDR KPRVTGQSAQ TYISPLLAKV FANAEGYADK LKDEYVSTEH LLLALSESKD
130 140 150 160 170 180
ETGELLRSRG INLKNLLSAL KEIRGNNRVT SENPESTFRS LEKFCRDLTQ LAKNEKIDPV
190 200 210 220 230 240
IGRDEEIRRV MQVLSRRTKN NPVLIGEPGV GKTAIVEGLA RRIVSGDVPD SLKGKRLLSL
250 260 270 280 290 300
DLGALVAGAK FRGEFEERLK AVISEVQKSE GRVILFIDEL HTLVGAGASE GSMDASNLLK
310 320 330 340 350 360
PALARGELRA IGATTLNEYR KYIEKDAALE RRFQQVYCPE PTVEDTIAIL RGLQEKYEVH
370 380 390 400 410 420
HGVRIRDEAL IAAAVLSNRY ITNRFLPDKA IDLVDEAASR LKMEIESQPV ELDQVERKIL
430 440 450 460 470 480
QLNIEKVSIG KENDTASKER LLKLEEELAE LSSKRNAMQA QWQNEKARIN ESRKYKEELE
490 500 510 520 530 540
QLRIEETKYS REGNLNKAAE LKYGKIPELE KKIAAVTAEL EKKAGQQGQL LREEVCEEDI
550 560 570 580 590 600
ARIVSMWTGI PVAKMLASEM QKFLQLEKVL QARVVGQDEA VRVVSDAIRR NKAGLSDMNR
610 620 630 640 650 660
PLGSFLCIGP TGVGKTELAR TLADFLFNDE KALTRIDMSE YMEKHSVSRL IGAPPGYVGY
670 680 690 700 710 720
DEGGQLTEAV RRRPYSVILF DEIEKAHQDV FNVFLQILDD GRLTDGQGRV VDFKNTIIIM
730 740 750 760 770 780
TSNIGSEYIL TAKDMGSIKE EINQILRDNF RPEFLNRIDE ILTFNRLEKE HIRKIVDIQL
790 800 810 820 830 840
RSVAERLQAR RLGLKVSDKA KDFLADIGYD PMFGARPLKR AIQAELENKL AREVLEGKFP
850
EGSTILVDKG ENSLIFKKG