Q72KE8
Gene name |
infB |
Protein name |
Translation initiation factor IF-2 |
Names |
|
Species |
Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) |
KEGG Pathway |
tth:TT_C0347 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q72KE8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q72KE8-F1 | Predicted | AlphaFoldDB |
No variants for Q72KE8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q72KE8 | |||||
No associated diseases with Q72KE8
5 regional properties for Q72KE8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 71 - 239 | IPR000795 |
| domain | Small GTP-binding protein domain | 74 - 230 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 1 - 48 | IPR006847 |
| domain | Translation initiation factor IF- 2, domain 3 | 348 - 462 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 247 - 335 | IPR044145 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKVRIYQLA | KELGMETQEL | LELLDQMGVA | YKSHASTLEE | KDAEAVRELV | KEQRGLQEKL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AEEERRKSLP | RRPPVVVIMG | HVDHGKTTLL | DYLRKSRIAE | KEAGGITQHV | GAFEVKTPQG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TVVFIDTPGH | EAFTTIRQRG | AKVADIAVIV | IAADDGIMPQ | TEEAIAHAKA | AGAKLIFAIN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KIDLPQADPE | KVKRQLMERG | FVPEEYGGDA | IVIPISAKTG | QGVQDLLEMI | LLLAELEDYR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ADPNAEPRGV | ILESKLDKQA | GIIANMLVQE | GTFRVGDYVV | AGEAYGRIRA | MMDADGNQRK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EAGPGSAVQV | LGFQELPHAG | DVVEWVPDLE | AAKEIAEERK | EERKAREEEE | KARRPRTMAE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LLRAMQEEGR | KELNLILRAD | TQGSLEAIQH | ILARESTEDV | KINILLAQVG | APTESDVLLA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QTANAAILAF | GVNPPGSVKK | KAEEKGVLLK | TFRIIYDLVD | EVRNMVKGQR | EPQYKEEVLG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QAEVRAIFRL | PTGKQVAGCM | VTQGRIPRNA | EVRVLRDGQV | IWQGRIASLK | RFKEDVREVA |
| 550 | 560 | 570 | |||
| QGYECGIGLD | GFDDFREGDV | IEAFQMVEVP | A |