Q72J92

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
KEGG Pathway
tth:TT_C0887
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

920-997 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q72J92

Entry ID Method Resolution Chain Position Source
AF-Q72J92-F1 Predicted AlphaFoldDB

No variants for Q72J92

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q72J92

No associated diseases with Q72J92

7 regional properties for Q72J92

Type Name Position InterPro Accession
domain SecA DEAD-like, N-terminal 5 - 396 IPR011115
domain SecA Wing/Scaffold 724 - 936 IPR011116
domain SecA, preprotein cross-linking domain 228 - 352 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 86 - 247 IPR014001
domain SecA motor DEAD 2 - 726 IPR014018
conserved_site SecA conserved site 570 - 585 IPR020937
domain SecA, C-terminal helicase domain 414 - 696 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGLLRRLFD NNEREIARYY KQVVEPVNRL EAEVEKLPDL AAAYRELKEK HEKGASLDEL
70 80 90 100 110 120
LPMAFALTRE SAKRYLGMRH FDVQLIGGAV LHEGKIAEMK TGEGKTLVAT LAVALNALTG
130 140 150 160 170 180
KGVHVVTVND YLARRDAEWM GPVYRGLGLS VGVIQHASTP AERRKAYLAD VTYVTNSELG
190 200 210 220 230 240
FDYLRDNMAI SPDQLVLRHD HPLHYAIIDE VDSILIDEAR TPLIISGPAE KATDLYYKMA
250 260 270 280 290 300
EIAKKLERGL PAEPGVRKEP TGDYTVEEKN RSVHLTLQGI AKAEKLLGIE GLFSPENMEL
310 320 330 340 350 360
AHMLIQAIRA KELYHRDRDY IVQDGQVIIV DEFTGRLMPG RRYGEGLHQA IEAKEGVRIE
370 380 390 400 410 420
RENQTLATIT YQNFFRLYEK RAGMTGTAKT EEKEFQEIYG MDVVVVPTNR PVVRKDFPDV
430 440 450 460 470 480
VYRTEKGKFY AVVEEIAEKY ERGQPVLVGT ISIEKSERLS QMLKEPRLYL PRLEMRLELF
490 500 510 520 530 540
KKASQKQQGP EWERLRKLLE RPAQLKDEDL APFEGLIPPK GNLRTAWEGL KRAVHTLAVL
550 560 570 580 590 600
RQGIPHQVLN AKHHAREAEI VAQAGRSKTV TIATNMAGRG TDIKLGGNPE YLAAALLEKE
610 620 630 640 650 660
GFDRYEWKVE LFIKKMVAGK EEEARALAQE LGIREELLER IREIREECKQ DEERVRALGG
670 680 690 700 710 720
LFIIGTERHE SRRIDNQLRG RAGRQGDPGG SRFYVSFDDD LMRLFASDRV IAMLDRMGFD
730 740 750 760 770 780
DSEPIEHPMV TRSIERAQKR VEDRNFAIRK QLLQFDDVLS RQREVIYAQR RLILLGKDEE
790 800 810 820 830 840
VKEAAIGMVE ETVASLAENF LNPEVHPEDW DLEGLKATLL DTAPQLQDFP FAELRALKAE
850 860 870 880 890 900
EAVERLVEAA LKAYEAREAE LSPPLMRAVE RFVILNVVDN AWKEHLHNLD VLRQGIFLRG
910 920 930 940 950 960
YGQKDPFQEY KIEATRLFNE MVAFIKSEVA KFLFRLKVEA EPVRPVREAP YVPVPEAKPE
970 980 990
PSEVFGVERK RATPPPQPGL SRAERRRLMR QEKKRKK