AiPD: Autoinhibited Protein Database

Gene name	rplB
Protein name	50S ribosomal protein L2
Names
Species	Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
KEGG Pathway	tth:TT_C1325
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-79 (Predicted disordered autoinhibitory region) PR

1-79 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
4V4I	X-ray	371 A	B	1-276	PDB
4V4J	X-ray	383 A	B	1-276	PDB
4V63	X-ray	321 A	BD/DD	1-276	PDB
4V67	X-ray	300 A	BD/DD	1-276	PDB
4V7P	X-ray	362 A	BC/CC	2-276	PDB
4V83	X-ray	350 A	BC/DC	2-272	PDB
4V84	X-ray	340 A	BC/DC	2-272	PDB
4V9J	X-ray	386 A	BD/DD	2-276	PDB
4V9K	X-ray	350 A	BD/DD	2-276	PDB
4V9L	X-ray	350 A	BD/DD	2-276	PDB
4V9M	X-ray	400 A	BD/DD	2-276	PDB
4V9N	X-ray	340 A	BD/DD	2-272	PDB
4V9Q	X-ray	340 A	AD/CD	2-272	PDB
4W29	X-ray	380 A	BD/DD	2-276	PDB
4XEJ	X-ray	380 A	AL02/BL02	2-272	PDB
5J4D	X-ray	310 A	E/JB	2-276	PDB
5V8I	X-ray	325 A	1D/2D	1-276	PDB
6B4V	X-ray	340 A	E/IB	2-276	PDB
6BOH	X-ray	340 A	E/JB	2-276	PDB
6BOK	X-ray	355 A	E/HB	2-276	PDB
6N1D	X-ray	320 A	AL02/BL02	1-276	PDB
AF-Q72I07-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
No variants for Q72I07

Type	Name	Position	InterPro Accession
domain	Ribosomal Proteins L2, RNA binding domain	42 - 118	IPR022666
domain	Ribosomal protein L2, C-terminal	125 - 253	IPR022669
conserved_site	Ribosomal protein L2, conserved site	219 - 230	IPR022671

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
large ribosomal subunit	The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).

Name	Definition
rRNA binding	Binding to a ribosomal RNA.
structural constituent of ribosome	The action of a molecule that contributes to the structural integrity of the ribosome.
transferase activity	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

Name	Definition
translation	The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins