Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q72HM1

Entry ID Method Resolution Chain Position Source
AF-Q72HM1-F1 Predicted AlphaFoldDB

No variants for Q72HM1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q72HM1

No associated diseases with Q72HM1

6 regional properties for Q72HM1

Type Name Position InterPro Accession
domain HD/PDEase domain 386 - 492 IPR003607
domain K Homology domain 262 - 329 IPR004087
domain K Homology domain, type 1 266 - 324 IPR004088
domain HD domain 390 - 483 IPR006674
domain HDIG domain 386 - 461 IPR006675
domain Ribonuclease Y, N-terminal 130 - 258 IPR022711

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLLDLVLLL LVLGLGGVLL LRRKGEDRSA QEARELLEAA RREAREVLEA ARKEARDILE
70 80 90 100 110 120
AARHEAKALR QEAEARAKAQ REEVEAELRR RLEAAEAEAK KRLEEAGERL KAEREELRAE
130 140 150 160 170 180
RERLRSLQEE LKEERERLKA EREELRREGE RLAKRAEALD ARAARLEEAE AELVRKEEAL
190 200 210 220 230 240
KAEARALEER FKEVERRLYE VAGLTPEEAR RLVLERLDRE LEEEKAQRVR AALERARLEA
250 260 270 280 290 300
RREAQKILAQ AMQRQASETA AQLAVTVVPI PSDAMKGRII GREGRNIRAF EALTGVDLII
310 320 330 340 350 360
DDTPDAVLLS SFNPIRREIA RMALEELLKD GRIHPSRIEE VVEKAKQEMK TFIYERGEEA
370 380 390 400 410 420
ALEAGVVGLK PGLIQLLGRL HFRSSYGQNV LKHSIQVAHL AGIMAAELGL DAALARRAGL
430 440 450 460 470 480
LHDIGKSVDR EVEGSHVEIG IALARRFGEP MEVVDAIAHH HDPDNAETLY AVLVAAADAL
490 500 510 520 530 540
SAARPGARRE SLEEYLQRLE ALERIALSFP GVETAFAVQA GREVRVIVKP EKISDAKATL
550 560 570
LAREIASRIE KEMNYPGQVQ VTVVRETRAV EYAR