Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q726P7

Entry ID Method Resolution Chain Position Source
AF-Q726P7-F1 Predicted AlphaFoldDB

No variants for Q726P7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q726P7

No associated diseases with Q726P7

5 regional properties for Q726P7

Type Name Position InterPro Accession
domain Peptidase M41 409 - 600 IPR000642
domain AAA+ ATPase domain 187 - 327 IPR003593
domain ATPase, AAA-type, core 191 - 324 IPR003959
conserved_site ATPase, AAA-type, conserved site 295 - 313 IPR003960
domain AAA ATPase, AAA+ lid domain 349 - 391 IPR041569

Functions

Description
EC Number 3.6.5.4 Acting on GTP; involved in cellular and subcellular movement
Subcellular Localization
  • Cell inner membrane; Peripheral membrane protein; Cytoplasmic side
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intrinsic component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

1 GO annotations of biological process

Name Definition
SRP-dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGFFSAIKRL WKGDTAPEDV SKPVEAEGSA IVGTSSTGSP VGTGAAMPAA QDAPSPAAPH
70 80 90 100 110 120
AIATPDDAVP DDAVPDDAVH GGEAPWKTEL TLALRQAEPR LSVWLGHVLD GVDEAGPILW
130 140 150 160 170 180
ERLRFFFSSL EVPADEAETF VRDFGRWLEA MEYRYVADFR SELQYRLALA LDLEDEEDER
190 200 210 220 230 240
SRLMLKLTEG LARTREQIGR RIDGLLASHG RIDEGFWEEL EEILIMADVG FEPTTQLIGR
250 260 270 280 290 300
LRERARKAGT DDPARFRELL REELEVIFRA PRRIAAVNPP EVVLLIGVNG VGKTTTIAKL
310 320 330 340 350 360
AYRAQLQGRK VLIAAGDTFR AAAIEQLEIW AKRVGAGFYA KTAGADPAAV AYEAMDKAVS
370 380 390 400 410 420
EGYDLLLVDT AGRLHTKANL MEELHKIRKV LGRKHPGAPH RSILVIDATT GQNALSQTKL
430 440 450 460 470 480
FNEACGVDEI VLTKLDGTAK GGIVVAVAMQ FGIPITYVGL GEKMEDMRPF NGSDFAMALL
GVEEKPAA