Q6ZVW7

PR
Gene name
IL17REL
Protein name
Putative interleukin-17 receptor E-like
Names
IL-17 receptor E-like, IL-17RE-like
Species
Homo sapiens (Human)
KEGG Pathway
hsa:400935
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

267-336 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6ZVW7

Entry ID Method Resolution Chain Position Source
AF-Q6ZVW7-F1 Predicted AlphaFoldDB

2 variants for Q6ZVW7

Variant ID(s) Position Change Description Diseaes Association Provenance
CA325474345
rs9617090
VAR_061187
 70 G>R No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD
VAR_039957
CA10301780
rs5771069
 333 L>P No ClinGen
UniProt
1000Genomes
ESP
ExAC
TOPMed
dbSNP
gnomAD

No associated diseases with Q6ZVW7

1 regional properties for Q6ZVW7

Type Name Position InterPro Accession
domain Interleukin-17 receptor C/E, N-terminal 55 - 292 IPR027841

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
interleukin-17 receptor activity Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8NFR9 IL17RE Interleukin-17 receptor E Homo sapiens (Human) PR
10 20 30 40 50 60
MSRSVLEALT SSTAMQCVPS DGCAMLLRVR ASITLHERLR GLEACAMSLD TQETQCQSVW
70 80 90 100 110 120
VARASHRQQG GQQLQVHFGC FAVSVAQHLY VTLRTIPHFC GVQLDQRHLV EAGKLSYWVD
130 140 150 160 170 180
RRRKAILVQV PRASGSPDYY LRLCLKRFTC EDAGAPVRVT ANSVSQAVFL PYSQELPCLC
190 200 210 220 230 240
LEGWSATPDA VRIQICPFEN DTEALEVLWD TVYYHPESQT LSWEPACPVS GHVSLCWRPG
250 260 270 280 290 300
PGAGCRKLQQ SSQLVHRRVQ YPLVDTQPQL CLKFSTSWGS WVRCPFEQRR FPTPPTSRCT
310 320 330
CVTGGSHSSL PANAHSRPAR SLQPQVTWQP PLLLPS