Q6ZMT9
PR
Gene name |
DTHD1 |
Protein name |
Death domain-containing protein 1 |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:401124 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6ZMT9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6ZMT9-F1 | Predicted | AlphaFoldDB |
618 variants for Q6ZMT9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
RCV001340506 rs758011674 RCV002546900 CA2885608 |
235 | F>L | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
CA95771835 RCV001300559 RCV002541930 rs1006425300 |
358 | D>V | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
RCV001234640 RCV002563245 rs773778842 CA2885645 |
383 | P>S | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV002554611 CA95771928 RCV001070894 rs746352706 |
386 | L>W | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
CA2885648 RCV002553819 RCV001056909 rs750097471 |
401 | S>Y | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
RCV002567911 RCV001237382 CA95784031 rs375987946 |
561 | Q>E | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP TOPMed dbSNP gnomAD |
|
CA2885720 RCV003166883 RCV001322806 rs371705837 |
615 | G>R | Inborn genetic diseases [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
RCV001074604 CA2885743 RCV001459081 rs144952478 |
704 | R>S | Retinal dystrophy [ClinVar] | Yes |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
CA356677390 rs1433993851 |
2 | H>Q | No |
ClinGen TOPMed |
|
|
CA356677388 rs1435895900 |
2 | H>R | No |
ClinGen gnomAD |
|
|
CA95763510 rs918419490 |
2 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs1318959750 CA356677397 |
3 | D>V | No |
ClinGen gnomAD |
|
|
rs1269510622 CA356677410 |
5 | C>G | No |
ClinGen TOPMed |
|
|
rs931094405 CA95763515 |
6 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs931094405 CA356677419 |
6 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
CA95763523 rs896536189 |
9 | Q>* | No |
ClinGen TOPMed |
|
|
rs1225064311 CA356677439 |
9 | Q>H | No |
ClinGen gnomAD |
|
|
CA95763530 rs896536189 |
9 | Q>K | No |
ClinGen TOPMed |
|
|
CA356677444 rs1335180792 |
10 | T>K | No |
ClinGen gnomAD |
|
|
CA2885555 rs761331682 |
10 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs1186648943 CA356677452 |
11 | M>I | No |
ClinGen TOPMed gnomAD |
|
|
CA2885556 rs766535142 |
11 | M>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1270880384 CA356677449 |
11 | M>T | No |
ClinGen gnomAD |
|
|
CA356677447 rs766535142 |
11 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1330678038 CA356677461 |
13 | S>A | No |
ClinGen gnomAD |
|
|
rs776819665 CA2885557 |
17 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1232018125 CA356677497 |
18 | K>T | No |
ClinGen TOPMed |
|
|
rs1190168085 CA356677515 |
21 | D>Y | No |
ClinGen gnomAD |
|
|
CA356677533 rs1305228235 |
23 | A>G | No |
ClinGen TOPMed |
|
|
rs187599064 CA95763546 |
24 | A>S | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA95763552 rs942393577 |
25 | R>K | No |
ClinGen TOPMed |
|
|
CA356677546 rs16992035 VAR_046339 CA2885559 |
26 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD UniProt dbSNP |
|
|
rs1163130827 CA356677556 |
27 | E>V | No |
ClinGen gnomAD |
|
|
CA95763562 rs902097477 |
29 | N>Y | No |
ClinGen TOPMed |
|
|
CA95763568 rs933522655 |
30 | V>G | No |
ClinGen TOPMed |
|
|
CA2885560 rs752863583 |
31 | I>L | No |
ClinGen ExAC gnomAD |
|
|
CA2885561 rs754011773 |
31 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1454445191 CA356677579 |
31 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA95763585 rs1042610989 |
33 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
CA2885562 rs767353519 |
33 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs545878482 CA2885563 |
34 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs902664539 CA95763593 |
35 | T>A | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 37 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA356677624 rs1291149455 |
39 | T>K | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 40 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1484471310 CA356677634 |
40 | N>K | No |
ClinGen TOPMed |
|
|
CA356677639 rs1282003092 |
41 | G>A | No |
ClinGen TOPMed |
|
|
CA356677637 rs1351954822 |
41 | G>R | No |
ClinGen gnomAD |
|
|
rs1297710872 CA356677651 |
43 | E>A | No |
ClinGen TOPMed |
|
|
CA356677650 rs748785345 |
43 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748785345 CA2885566 |
43 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1347895911 CA356677666 |
45 | H>N | No |
ClinGen gnomAD |
|
|
CA2885567 rs754479458 |
45 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754479458 CA356677667 |
45 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA95763617 rs1000726911 |
46 | Y>H | No |
ClinGen TOPMed gnomAD |
|
|
CA95763647 rs796663653 |
47 | T>P | No |
ClinGen Ensembl |
|
|
rs1254334572 CA356677762 |
58 | H>R | No |
ClinGen gnomAD |
|
|
CA356677772 rs1429363909 |
59 | M>I | No |
ClinGen TOPMed |
|
|
CA356677767 rs1306339261 |
59 | M>V | No |
ClinGen TOPMed |
|
| TCGA novel | 61 | S>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA356677794 rs1181298328 |
62 | A>G | No |
ClinGen gnomAD |
|
|
CA356677795 rs1362183774 |
63 | L>I | No |
ClinGen TOPMed gnomAD |
|
|
CA95763654 rs562970570 |
67 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
CA95763664 rs956537083 |
69 | N>K | No |
ClinGen gnomAD |
|
|
rs975899908 CA95763680 |
70 | T>I | No |
ClinGen gnomAD |
|
|
rs1032443046 CA95763694 |
71 | S>L | No |
ClinGen TOPMed |
|
|
rs1560782478 CA356677874 |
74 | G>V | No |
ClinGen Ensembl |
|
|
CA95763698 rs747817328 |
75 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752476393 CA2885572 |
75 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747817328 CA2885571 |
75 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1333552186 CA356677878 |
76 | V>I | No |
ClinGen gnomAD |
|
| TCGA novel | 77 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs192124414 CA95763706 |
78 | G>V | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs1283049028 CA356677916 |
81 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs1277238800 CA356677915 |
81 | E>V | No |
ClinGen gnomAD |
|
|
CA95763722 rs970653490 |
82 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
CA95763729 rs1025922156 |
87 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs908859456 CA95763732 |
88 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA356678004 rs1394517583 |
93 | N>K | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 94 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1205348690 CA356678044 |
98 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1171662123 CA356678050 |
99 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA356678054 rs1390192198 |
100 | E>Q | No |
ClinGen TOPMed |
|
|
CA95763741 rs984331303 |
102 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
rs116402730 CA2885577 |
105 | E>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1297308125 CA356678098 |
106 | N>H | No |
ClinGen gnomAD |
|
|
rs1038624277 CA356678103 |
106 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA356678122 rs1287255876 |
109 | G>A | No |
ClinGen Ensembl |
|
|
rs547413369 CA95763755 |
111 | R>K | No |
ClinGen Ensembl |
|
|
CA356678160 rs1442564997 |
114 | T>I | No |
ClinGen gnomAD |
|
|
CA356678161 rs1326030058 |
115 | H>N | No |
ClinGen gnomAD |
|
|
CA356678168 rs1369548958 |
115 | H>Q | No |
ClinGen gnomAD |
|
|
rs1449311713 CA356678176 |
117 | I>V | No |
ClinGen TOPMed |
|
|
CA95763757 rs930144559 |
120 | T>K | No |
ClinGen TOPMed |
|
|
rs184173479 CA2885578 |
121 | T>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA356678213 rs1298332099 |
122 | E>D | No |
ClinGen gnomAD |
|
|
CA356678210 rs1336901301 |
122 | E>G | No |
ClinGen TOPMed |
|
|
CA2885579 rs765242624 |
123 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 125 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1227530252 CA356678249 |
127 | E>D | No |
ClinGen TOPMed |
|
|
rs1227171514 CA356678247 |
127 | E>G | No |
ClinGen gnomAD |
|
|
rs377740589 CA356678255 |
128 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs377740589 CA2885580 |
128 | T>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA356678283 rs1214501429 |
132 | P>L | No |
ClinGen gnomAD |
|
|
rs1578430603 CA356678319 |
137 | T>N | No |
ClinGen Ensembl |
|
|
CA95763808 rs1031670278 |
138 | T>A | No |
ClinGen Ensembl |
|
|
rs896581316 CA95763814 |
138 | T>I | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 139 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA356678339 rs1443699061 |
141 | I>V | No |
ClinGen TOPMed |
|
|
CA356678349 rs1191747484 |
142 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA356678353 rs1421559253 |
143 | C>R | No |
ClinGen gnomAD |
|
|
CA95763835 rs1042634650 |
144 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs924160976 CA95763840 |
145 | I>N | No |
ClinGen TOPMed |
|
|
CA2885581 rs763224410 |
147 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA95763850 rs868641702 |
150 | I>T | No |
ClinGen gnomAD |
|
|
CA356678410 rs1462708878 |
151 | N>Y | No |
ClinGen gnomAD |
|
|
rs1326138751 CA356678418 |
152 | S>G | No |
ClinGen gnomAD |
|
|
CA2885582 rs767273674 |
152 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1054325137 CA95763887 |
156 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA356678455 rs1476850200 |
157 | D>E | No |
ClinGen TOPMed |
|
|
CA356678453 rs1234177584 |
157 | D>V | No |
ClinGen gnomAD |
|
|
CA356678450 rs1337384038 |
157 | D>Y | No |
ClinGen gnomAD |
|
|
CA356678458 rs1272782694 |
158 | S>A | No |
ClinGen gnomAD |
|
|
rs1218051837 CA356678481 |
161 | I>T | No |
ClinGen gnomAD |
|
|
rs766301788 CA2885586 |
161 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356678495 rs1193681989 |
163 | H>P | No |
ClinGen TOPMed |
|
|
CA356678507 rs1486170259 |
164 | K>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA356678505 rs1469456443 |
164 | K>R | No |
ClinGen TOPMed |
|
|
rs1000778156 CA95763909 |
165 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA95763924 rs956587496 |
167 | I>M | No |
ClinGen Ensembl |
|
|
CA95763916 rs1030877579 |
167 | I>V | No |
ClinGen TOPMed |
|
| TCGA novel | 169 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs895240671 CA95763927 |
171 | E>* | No |
ClinGen TOPMed |
|
|
rs895240671 CA356678553 |
171 | E>K | No |
ClinGen TOPMed |
|
|
CA2885591 rs758173315 |
173 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA95767202 rs923621523 |
174 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
CA2885592 rs187188942 |
176 | L>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1408132132 CA356678601 |
177 | S>R | No |
ClinGen gnomAD |
|
|
rs1995319 CA356678619 |
179 | V>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_046340 CA2885594 rs1995319 |
179 | V>D | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1995319 CA356678620 |
179 | V>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA2885593 rs200576831 |
179 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356678630 rs1435807760 |
181 | G>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1271869000 CA356678638 |
182 | P>H | No |
ClinGen TOPMed |
|
|
CA356678633 rs1339916414 |
182 | P>T | No |
ClinGen TOPMed |
|
|
rs1373972676 CA356678641 |
183 | Q>* | No |
ClinGen gnomAD |
|
| TCGA novel | 183 | Q>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs77539527 CA2885596 |
184 | V>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs781680006 CA2885595 |
184 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs781680006 CA356678647 |
184 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA356678662 rs1560786736 |
186 | C>Y | No |
ClinGen Ensembl |
|
|
rs1454762714 CA356678670 |
187 | Y>C | No |
ClinGen TOPMed |
|
|
rs1353036946 CA356678693 |
191 | P>A | No |
ClinGen TOPMed |
|
|
CA2885597 rs769909057 |
192 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA356678704 rs1350001780 |
193 | Y>H | No |
ClinGen TOPMed gnomAD |
|
|
rs889893449 CA95767260 |
194 | V>A | No |
ClinGen Ensembl |
|
|
CA2885598 rs775590360 |
194 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1279403722 CA356678715 |
195 | L>I | No |
ClinGen gnomAD |
|
|
rs1206265525 CA356678748 |
199 | E>D | No |
ClinGen gnomAD |
|
| TCGA novel | 200 | C>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs530789646 CA95767273 |
200 | C>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs369825204 CA356678756 |
201 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA95767277 RCV001317806 rs781043052 |
201 | R>Q | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
rs369825204 CA2885600 |
201 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs994537356 CA95767288 |
202 | I>K | No |
ClinGen TOPMed |
|
|
rs1253337546 CA356678761 |
202 | I>L | No |
ClinGen gnomAD |
|
|
CA95767290 rs1034908342 |
203 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA356678803 rs200560913 |
207 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
CA356678808 rs1173534348 |
208 | S>Y | No |
ClinGen gnomAD |
|
|
rs1393697366 CA356678829 |
211 | V>A | No |
ClinGen gnomAD |
|
|
CA95767318 rs774590229 |
212 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2885601 rs774590229 |
212 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356678836 RCV001056780 rs1329859259 |
213 | D>Y | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA95767323 rs552426120 |
214 | N>D | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA2885602 rs377093636 |
217 | L>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs377093636 CA356678868 |
217 | L>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| rs1440209090 | 218 | V>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1371791043 CA356678885 |
219 | S>R | No |
ClinGen gnomAD |
|
|
rs570690508 CA95767363 |
220 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs201684570 CA95767372 |
221 | V>I | No |
ClinGen gnomAD |
|
|
rs753801171 CA2885604 |
222 | I>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356678902 rs753801171 |
222 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356678922 rs1191668665 |
225 | E>A | No |
ClinGen gnomAD |
|
|
rs1436892020 CA356678930 |
226 | C>F | No |
ClinGen TOPMed gnomAD |
|
|
rs1436892020 CA356678928 |
226 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs764781084 CA2885606 |
227 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1254386766 CA356678938 |
228 | D>N | No |
ClinGen gnomAD |
|
|
rs761582083 CA2885607 |
229 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356678967 rs1405283199 |
231 | K>N | No |
ClinGen TOPMed |
|
|
rs534797041 CA356678983 |
234 | P>S | No |
ClinGen 1000Genomes gnomAD |
|
|
rs534797041 CA95767452 |
234 | P>T | No |
ClinGen 1000Genomes gnomAD |
|
|
CA2885609 rs777500108 |
237 | I>T | No |
ClinGen ExAC TOPMed |
|
|
rs1560787116 CA356679016 |
239 | I>T | No |
ClinGen Ensembl |
|
|
CA356679034 rs1464309874 |
242 | P>S | No |
ClinGen gnomAD |
|
|
rs1167333045 CA356679054 |
245 | A>S | No |
ClinGen gnomAD |
|
|
rs1395400652 CA356679059 |
246 | R>C | No |
ClinGen gnomAD |
|
|
rs139675396 CA2885610 |
246 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
RCV001294771 CA356679074 rs1323909494 |
248 | R>I | No |
ClinGen ClinVar dbSNP gnomAD |
|
|
CA356679081 rs1329280463 |
249 | G>E | No |
ClinGen gnomAD |
|
|
CA356679100 rs1560787195 |
252 | R>G | No |
ClinGen Ensembl |
|
| TCGA novel | 253 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1031127454 CA95767494 |
254 | I>S | No |
ClinGen TOPMed |
|
|
RCV001309751 CA2885612 rs757624730 |
255 | M>T | No |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
|
rs781472337 CA2885613 |
258 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1274655498 RCV001232430 CA356679160 |
260 | D>G | No |
ClinGen ClinVar dbSNP gnomAD |
|
|
rs1334979739 CA356679187 |
264 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
RCV001216330 rs879092621 CA95767523 |
268 | L>P | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA95767510 rs746350889 |
268 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1346627184 CA356679232 |
271 | N>H | No |
ClinGen TOPMed |
|
|
rs1449263131 CA356679242 |
272 | S>A | No |
ClinGen TOPMed gnomAD |
|
|
CA2885615 rs770256085 |
275 | G>E | No |
ClinGen ExAC gnomAD |
|
|
rs149774893 CA2885616 |
277 | K>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA356679276 rs1429010815 |
277 | K>T | No |
ClinGen TOPMed |
|
|
CA356679285 rs1560787332 |
278 | G>E | No |
ClinGen Ensembl |
|
|
rs1418867635 CA356679290 |
279 | G>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1190409837 CA356679286 |
279 | G>S | No |
ClinGen gnomAD |
|
|
COSM1177786 COSM1177787 rs1418867635 CA356679291 |
279 | G>V | endometrium [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA356679320 rs1417711056 |
282 | G>R | No |
ClinGen gnomAD |
|
|
CA356679324 rs1176561094 |
282 | G>V | No |
ClinGen gnomAD |
|
|
rs765224946 RCV001229119 CA2885624 |
283 | T>N | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
rs765224946 CA356679328 |
283 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356679338 rs1417476141 |
285 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
RCV001229120 CA95770526 rs898541301 |
287 | V>L | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
| TCGA novel | 288 | K>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1045636239 CA95770546 |
288 | K>R | No |
ClinGen gnomAD |
|
|
rs1578441043 CA356679366 |
289 | V>A | No |
ClinGen Ensembl |
|
|
CA95770571 rs376079497 |
293 | G>C | No |
ClinGen TOPMed gnomAD |
|
|
CA356679392 rs376079497 |
293 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
CA95770576 rs907090390 |
294 | I>F | No |
ClinGen Ensembl |
|
|
rs1438592173 CA356679406 |
295 | F>S | No |
ClinGen TOPMed |
|
|
rs1275429559 CA356679416 |
297 | V>I | No |
ClinGen TOPMed |
|
| TCGA novel | 298 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 302 | K>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA95770578 rs1028741383 |
305 | S>L | No |
ClinGen TOPMed |
|
|
rs1278377276 CA356679491 |
307 | T>I | No |
ClinGen gnomAD |
|
|
CA356679508 rs1273907656 |
310 | K>R | No |
ClinGen TOPMed |
|
|
RCV001307098 CA2885626 rs754906230 |
311 | K>E | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
RCV001213013 CA356679522 rs1056021890 |
312 | G>A | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA356679523 rs1056021890 |
312 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
CA95770607 RCV001296743 rs1056021890 |
312 | G>V | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
rs1281549097 CA356679526 |
313 | L>F | No |
ClinGen gnomAD |
|
|
CA356679530 RCV001297843 rs1199013078 |
314 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ClinVar NCI-TCGA TOPMed dbSNP gnomAD |
|
CA95770617 rs182788481 |
316 | K>N | No |
ClinGen 1000Genomes |
|
|
CA356679559 rs1181185650 |
318 | S>T | No |
ClinGen gnomAD |
|
|
CA95770633 rs372924892 |
319 | M>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs372924892 CA2885629 |
319 | M>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA2885628 rs372924892 |
319 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1437773676 CA356679571 |
320 | D>N | No |
ClinGen gnomAD |
|
|
COSM1429500 COSM1429499 rs970203447 CA95770650 |
322 | R>* | large_intestine [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
CA95770658 rs979831227 |
322 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA356679590 rs1176383285 |
323 | I>T | No |
ClinGen TOPMed |
|
|
CA2885630 RCV001213529 rs542623785 |
324 | S>C | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA356679596 rs542623785 |
324 | S>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1196956846 CA356679602 |
325 | L>* | No |
ClinGen TOPMed |
|
|
rs1300802979 CA356679607 |
326 | N>H | No |
ClinGen gnomAD |
|
|
CA2885631 rs560693384 |
328 | P>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA2885632 rs756535211 |
329 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA2885633 rs780475018 |
331 | V>F | No |
ClinGen ExAC gnomAD |
|
|
rs1304808677 CA356679650 |
333 | T>P | No |
ClinGen TOPMed gnomAD |
|
|
CA356679682 rs1215696085 |
338 | V>E | No |
ClinGen TOPMed |
|
|
rs928276724 CA95770719 |
340 | L>I | No |
ClinGen TOPMed |
|
|
rs1190199905 CA356679730 |
343 | Q>R | No |
ClinGen gnomAD |
|
|
rs1172272567 CA356679742 |
345 | V>L | No |
ClinGen TOPMed |
|
|
CA2885640 RCV001240707 rs745581607 |
346 | D>E | No |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
|
rs563179017 CA2885639 RCV001319720 |
346 | D>G | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
rs866210741 CA95771709 |
346 | D>N | No |
ClinGen Ensembl |
|
|
rs1256384712 CA356679752 |
347 | P>S | No |
ClinGen gnomAD |
|
|
rs1256384712 CA356679753 |
347 | P>T | No |
ClinGen gnomAD |
|
|
rs1417141248 CA356679771 |
350 | V>E | No |
ClinGen TOPMed |
|
|
rs1473632537 CA356679786 |
352 | H>Q | No |
ClinGen TOPMed |
|
|
rs1214400915 CA356679780 |
352 | H>Y | No |
ClinGen gnomAD |
|
|
rs769724268 CA356679793 |
353 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2885642 rs775552771 |
356 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1428896067 CA356679842 |
360 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
CA356679850 rs1211959107 |
361 | Y>S | No |
ClinGen TOPMed |
|
|
CA356679856 rs1192564295 |
362 | S>L | No |
ClinGen gnomAD |
|
|
CA95771871 rs199975273 |
365 | S>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs1462635084 CA356679885 |
367 | S>G | No |
ClinGen gnomAD |
|
|
CA95771913 rs866698643 |
368 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA95771910 rs866698643 |
368 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
CA356679902 rs1353322798 |
370 | I>V | No |
ClinGen gnomAD |
|
|
rs1456885585 CA356679925 |
373 | Q>* | No |
ClinGen gnomAD |
|
|
CA356679927 rs1291112440 |
373 | Q>R | No |
ClinGen gnomAD |
|
|
rs1363164441 CA356679935 |
374 | H>R | No |
ClinGen gnomAD |
|
|
TCGA novel rs1756301984 RCV001202758 |
375 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinVar NCI-TCGA dbSNP |
|
rs1027656421 CA95771917 |
376 | S>* | No |
ClinGen TOPMed |
|
|
CA2885644 rs776034617 |
376 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1312897755 CA356679963 |
379 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA95771921 rs958801424 |
382 | K>T | No |
ClinGen Ensembl |
|
|
rs912711755 CA95771950 |
393 | Y>H | No |
ClinGen TOPMed |
|
|
rs1407022059 CA356680076 |
395 | D>E | No |
ClinGen TOPMed |
|
|
CA356680069 rs1354281497 |
395 | D>N | No |
ClinGen gnomAD |
|
|
rs533626351 CA2885646 |
398 | N>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1319967224 CA356680101 |
399 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs767042064 CA2885647 |
400 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356680107 rs1219372004 |
400 | G>R | No |
ClinGen gnomAD |
|
|
RCV001065188 rs767042064 CA95771973 |
400 | G>V | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
rs756413588 CA2885649 |
403 | I>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756413588 CA95772004 |
403 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1215637414 CA356680124 |
403 | I>V | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 404 | D>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA356680133 rs1475997164 |
404 | D>E | No |
ClinGen gnomAD |
|
|
CA95772014 rs1013364174 |
404 | D>N | No |
ClinGen Ensembl |
|
| TCGA novel | 405 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1445837636 CA356680151 |
407 | R>G | No |
ClinGen TOPMed |
|
|
CA2885651 rs754339190 |
408 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356680171 rs1421528220 |
410 | S>G | No |
ClinGen gnomAD |
|
|
rs1160579316 CA356680175 |
410 | S>N | No |
ClinGen gnomAD |
|
|
rs755519744 CA2885652 |
412 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1419583501 CA356680187 |
412 | T>R | No |
ClinGen gnomAD |
|
|
CA356680191 rs1296473892 |
413 | I>V | No |
ClinGen Ensembl |
|
|
CA2885653 rs779417332 |
414 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA95772066 rs1043055500 |
416 | I>V | No |
ClinGen TOPMed |
|
|
rs748136362 CA2885654 |
417 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA2885655 rs758507951 |
417 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356680218 rs758507951 |
417 | T>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs977339400 CA356680221 |
418 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs977339400 CA95772091 |
418 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1225555418 CA356680230 |
419 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1343413930 CA356680226 |
419 | S>P | No |
ClinGen TOPMed |
|
|
CA95772126 rs776388146 |
420 | Y>F | No |
ClinGen Ensembl |
|
|
CA356680245 rs1578442777 |
421 | F>L | No |
ClinGen Ensembl |
|
|
rs769705093 CA2885658 |
423 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs189410090 RCV001047972 CA2885657 |
423 | R>W | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
rs887026078 CA95782121 |
424 | T>K | No |
ClinGen TOPMed |
|
|
rs551082542 CA2885664 |
427 | A>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA356680291 rs1410965995 |
427 | A>S | No |
ClinGen TOPMed |
|
|
rs551082542 CA356680293 |
427 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA356680300 rs1186343583 |
429 | I>L | No |
ClinGen gnomAD |
|
|
rs1349892591 CA356680322 |
432 | P>T | No |
ClinGen gnomAD |
|
|
CA356680356 rs1310097041 |
436 | A>V | No |
ClinGen gnomAD |
|
|
rs1384198493 CA356680357 |
437 | S>R | No |
ClinGen TOPMed |
|
|
rs1238295638 CA356680389 |
441 | K>E | No |
ClinGen gnomAD |
|
|
CA356680401 rs1578456374 |
442 | L>F | No |
ClinGen Ensembl |
|
|
CA2885667 rs766699282 |
442 | L>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356680406 rs1446086665 |
443 | L>P | No |
ClinGen TOPMed |
|
|
CA356680429 rs1177375775 |
447 | S>G | No |
ClinGen gnomAD |
|
|
CA356680441 rs1255462068 |
448 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
CA356680445 rs1203275001 |
449 | D>H | No |
ClinGen TOPMed |
|
|
CA95782173 rs898297472 |
450 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
CA95782182 rs968579799 |
452 | W>C | No |
ClinGen gnomAD |
|
|
rs1578456441 CA356680474 |
453 | C>R | No |
ClinGen Ensembl |
|
|
CA356680509 rs1399733849 |
458 | V>I | No |
ClinGen gnomAD |
|
|
rs1444640290 CA356680519 |
459 | V>A | No |
ClinGen gnomAD |
|
|
CA356680538 rs890830046 |
462 | I>K | No |
ClinGen TOPMed gnomAD |
|
|
CA95782214 rs890830046 |
462 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1432391235 CA356680542 |
463 | Q>E | No |
ClinGen TOPMed gnomAD |
|
|
RCV001059412 rs188954144 CA356680555 |
464 | S>R | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA356680559 rs758028678 |
465 | G>A | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 465 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA95782232 RCV001058271 rs758028678 |
465 | G>D | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA2885671 rs373949236 |
465 | G>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs758028678 CA95782234 |
465 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA356680571 rs1365182232 |
467 | V>A | No |
ClinGen gnomAD |
|
|
rs1365182232 CA356680570 |
467 | V>G | No |
ClinGen gnomAD |
|
|
CA356680568 CA95782244 rs1019232421 |
467 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA95782258 rs765596905 |
468 | S>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2885672 rs765596905 |
468 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356680589 rs1316849434 |
470 | E>D | No |
ClinGen gnomAD |
|
|
CA2885674 rs777323018 |
477 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA356680638 rs777323018 |
477 | R>T | No |
ClinGen ExAC gnomAD |
|
|
CA356680668 rs1356400971 |
479 | I>M | No |
ClinGen gnomAD |
|
|
rs1294652107 CA356680663 |
479 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1209838308 CA356680671 |
480 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1209838308 CA356680669 |
480 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
rs781583416 CA2885679 RCV001061691 |
481 | L>P | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
rs749054756 CA2885680 |
482 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA95783840 rs376898600 |
483 | L>I | No |
ClinGen ESP TOPMed |
|
|
rs536272239 CA95783842 |
485 | S>F | No |
ClinGen 1000Genomes |
|
|
rs115555517 CA2885682 |
487 | M>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA95783849 rs140254738 |
487 | M>V | No |
ClinGen 1000Genomes |
|
|
CA95783882 rs1048544394 |
493 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA2885683 rs748178118 |
493 | V>I | No |
ClinGen ExAC gnomAD |
|
|
rs1161472061 CA356680769 |
495 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
rs771480211 CA2885684 |
498 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs1421402461 CA356680789 |
498 | S>Y | No |
ClinGen gnomAD |
|
|
CA356680800 rs1298607998 |
500 | E>Q | No |
ClinGen gnomAD |
|
|
CA356680809 rs1359642035 |
501 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
rs563835721 CA95783894 |
501 | E>G | No |
ClinGen Ensembl |
|
|
rs1397796968 CA356680815 |
502 | A>P | No |
ClinGen gnomAD |
|
|
CA95783918 COSM1727988 rs911353379 COSM1727989 |
508 | A>V | liver [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
rs942783392 CA95783920 |
509 | C>* | No |
ClinGen TOPMed |
|
|
rs1042448705 CA95783919 |
509 | C>R | No |
ClinGen Ensembl |
|
|
rs1340614999 CA356680872 |
510 | I>M | No |
ClinGen gnomAD |
|
|
rs1041114036 CA95783922 |
512 | L>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA356680906 rs1560800008 |
516 | K>E | No |
ClinGen Ensembl |
|
|
CA356680919 rs187161267 |
517 | D>E | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1382153900 CA356680913 |
517 | D>N | No |
ClinGen TOPMed |
|
|
rs770529433 CA2885687 |
518 | N>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770529433 CA356680925 |
518 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356680933 rs1167757549 |
519 | P>L | No |
ClinGen TOPMed |
|
|
rs1285802256 CA356680956 |
523 | A>P | No |
ClinGen gnomAD |
|
|
rs200787538 CA2885688 |
523 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
RCV001226165 CA356680962 rs1213359729 |
524 | V>L | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
rs759836208 CA2885689 |
525 | L>I | No |
ClinGen ExAC gnomAD |
|
|
CA356680980 RCV001207443 CA356680981 rs1185556863 RCV001035336 |
527 | V>L | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
rs1053903285 RCV001246840 CA95783939 |
528 | P>A | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA356681010 rs1379530079 |
531 | D>E | No |
ClinGen gnomAD |
|
|
CA95783941 rs868814877 |
531 | D>N | No |
ClinGen Ensembl |
|
|
rs1188093232 CA356681028 |
534 | Q>* | No |
ClinGen TOPMed |
|
|
rs1444118443 CA356681037 |
535 | V>E | No |
ClinGen TOPMed |
|
|
CA356681059 rs1248140317 |
538 | D>V | No |
ClinGen TOPMed |
|
|
rs1483490324 CA356681066 |
539 | L>R | No |
ClinGen TOPMed |
|
|
rs1276977603 CA356681067 |
540 | H>N | No |
ClinGen TOPMed |
|
|
rs201839505 CA95783950 |
543 | G>A | No |
ClinGen ESP ExAC gnomAD |
|
|
rs201839505 CA356681093 |
543 | G>E | No |
ClinGen ESP ExAC gnomAD |
|
|
CA2885693 rs201839505 |
543 | G>V | No |
ClinGen ESP ExAC gnomAD |
|
|
rs775716091 CA95783958 |
544 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1355649495 CA356681107 |
546 | G>R | No |
ClinGen TOPMed |
|
|
CA95783972 rs900726166 RCV001326279 |
547 | P>L | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA356681113 rs1352070477 |
547 | P>T | No |
ClinGen gnomAD |
|
|
CA2885694 rs374066496 |
548 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA95783992 rs1028369845 |
549 | E>K | No |
ClinGen gnomAD |
|
|
rs1034205141 CA95783994 |
550 | P>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 550 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs955067649 CA95783999 |
551 | S>C | No |
ClinGen gnomAD |
|
|
rs1252806260 CA356681136 |
551 | S>P | No |
ClinGen gnomAD |
|
|
CA2885695 rs12507599 VAR_046341 |
552 | R>C | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs369210518 CA2885696 |
552 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA95784014 rs961141007 |
555 | Q>H | No |
ClinGen gnomAD |
|
|
COSM1055020 COSM1055022 rs750691784 CA2885697 |
557 | R>* | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs61739432 CA2885698 |
557 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA356681184 rs1465269926 |
559 | G>R | No |
ClinGen gnomAD |
|
|
rs971700996 CA95784025 |
560 | E>* | No |
ClinGen TOPMed |
|
|
CA356681193 rs1560800339 |
560 | E>G | No |
ClinGen Ensembl |
|
|
rs971700996 CA356681191 |
560 | E>K | No |
ClinGen TOPMed |
|
|
CA356681198 rs375987946 |
561 | Q>* | No |
ClinGen 1000Genomes ESP TOPMed gnomAD |
|
|
CA356681207 rs778835630 |
562 | L>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2885699 rs778835630 |
562 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748005265 CA356681212 |
563 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA2885700 rs748005265 |
563 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA95784032 rs952996813 |
563 | L>V | No |
ClinGen TOPMed |
|
|
CA356681271 rs1578459835 |
572 | A>S | No |
ClinGen Ensembl |
|
|
RCV001227259 CA2885709 rs536385570 |
575 | N>D | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
rs555041609 CA356681307 |
575 | N>K | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs1560805953 CA356681305 |
575 | N>S | No |
ClinGen Ensembl |
|
|
rs1385467389 RCV001316875 CA356681309 |
576 | G>R | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA356681314 rs1578470919 |
576 | G>V | No |
ClinGen Ensembl |
|
|
CA95790214 rs865988968 |
578 | D>G | No |
ClinGen Ensembl |
|
|
rs866593789 CA95790228 |
579 | Y>S | No |
ClinGen Ensembl |
|
|
CA356681344 rs1341397305 |
581 | K>E | No |
ClinGen gnomAD |
|
|
CA356681352 rs1560806010 |
582 | D>A | No |
ClinGen Ensembl |
|
|
rs376420804 CA95790236 |
582 | D>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA2885710 RCV001340619 rs376420804 |
582 | D>N | No |
ClinGen ClinVar 1000Genomes ExAC TOPMed dbSNP gnomAD |
|
|
CA356681351 rs376420804 |
582 | D>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs775006590 CA2885711 |
583 | Y>C | No |
ClinGen ExAC |
|
|
CA356681357 rs1156490700 |
583 | Y>N | No |
ClinGen gnomAD |
|
|
rs563515929 CA95790240 |
584 | T>I | No |
ClinGen Ensembl |
|
|
rs752773624 CA95790250 |
585 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs752773624 CA356681370 |
585 | L>I | No |
ClinGen TOPMed gnomAD |
|
|
CA356681379 rs1223750814 |
586 | I>T | No |
ClinGen gnomAD |
|
|
CA356681392 rs1265971709 |
588 | H>R | No |
ClinGen gnomAD |
|
|
CA2885712 rs761928746 |
589 | L>S | No |
ClinGen ExAC gnomAD |
|
|
rs761928746 CA356681400 |
589 | L>W | No |
ClinGen ExAC gnomAD |
|
|
rs1207871495 CA356681426 RCV001224080 |
593 | P>T | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA2885713 rs537399211 |
594 | R>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1229629493 CA356681462 |
598 | Q>R | No |
ClinGen TOPMed |
|
|
rs374001739 CA95790256 |
599 | I>S | No |
ClinGen ESP TOPMed |
|
|
rs558904224 CA95790258 |
600 | K>E | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA356681488 rs1420932466 |
602 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs1560806151 CA356681505 |
604 | E>D | No |
ClinGen Ensembl |
|
|
CA95790296 rs1040447767 |
604 | E>Q | No |
ClinGen Ensembl |
|
|
rs60640167 CA2885716 |
608 | Y>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs929467367 CA95790303 |
609 | S>I | No |
ClinGen gnomAD |
|
|
CA356681544 rs1578471100 |
610 | C>R | No |
ClinGen Ensembl |
|
|
rs1361535637 CA356681546 |
610 | C>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA356681553 rs1167679211 |
611 | P>S | No |
ClinGen TOPMed |
|
|
CA356681561 rs1296566824 |
612 | H>R | No |
ClinGen gnomAD |
|
|
CA356681568 rs1228964739 |
613 | Y>C | No |
ClinGen gnomAD |
|
|
rs368573712 CA2885718 |
613 | Y>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1312038858 CA356681574 |
614 | K>E | No |
ClinGen gnomAD |
|
|
CA2885719 rs371705837 |
615 | G>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA95790313 rs1013119178 |
615 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
rs1013119178 CA356681582 |
615 | G>V | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 616 | T>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1287950284 CA356681594 |
617 | I>N | No |
ClinGen gnomAD |
|
|
CA2885721 rs756754406 |
618 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA356681601 rs1482331685 |
619 | V>I | No |
ClinGen TOPMed |
|
|
CA356681616 rs1215523979 |
621 | K>E | No |
ClinGen gnomAD |
|
|
CA95790334 rs904842690 |
622 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1240020133 CA356681632 |
623 | P>R | No |
ClinGen gnomAD |
|
|
rs1484278911 CA356681635 |
624 | K>E | No |
ClinGen TOPMed |
|
|
CA356681642 rs1483991186 |
625 | G>R | No |
ClinGen gnomAD |
|
|
CA356681667 rs1181971271 |
628 | V>A | No |
ClinGen gnomAD |
|
|
rs1181971271 CA356681666 |
628 | V>D | No |
ClinGen gnomAD |
|
|
CA95790339 rs867582414 |
629 | P>L | No |
ClinGen TOPMed |
|
|
rs1254808755 CA356681678 |
630 | N>S | No |
ClinGen gnomAD |
|
|
rs899302567 CA95790348 |
632 | N>S | No |
ClinGen Ensembl |
|
|
CA95790357 rs1003643045 |
634 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1234622329 CA356681717 |
636 | V>A | No |
ClinGen TOPMed |
|
|
CA2885723 RCV001063885 rs542659542 |
636 | V>I | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
CA2885722 rs542659542 RCV001212365 |
636 | V>L | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
CA356681723 rs1348534305 |
637 | I>T | No |
ClinGen TOPMed |
|
|
rs956671927 CA95790362 |
640 | N>S | No |
ClinGen Ensembl |
|
|
CA356681753 rs1410208985 |
641 | H>R | No |
ClinGen TOPMed |
|
|
CA95790380 rs879151758 |
643 | Q>L | No |
ClinGen Ensembl |
|
|
rs1355998435 CA356681784 |
646 | I>V | No |
ClinGen TOPMed |
|
|
rs769437545 CA2885724 RCV001227810 |
647 | C>F | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
rs1167162821 CA356681843 |
654 | P>Q | No |
ClinGen TOPMed |
|
|
CA356681842 rs1311358539 |
654 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs967915159 CA95790402 |
655 | K>N | No |
ClinGen Ensembl |
|
|
CA95790399 rs1006121164 |
655 | K>R | No |
ClinGen TOPMed |
|
|
CA356681866 rs1272884990 |
656 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA356681877 rs1377596348 |
657 | K>M | No |
ClinGen gnomAD |
|
|
CA95809776 rs577534478 |
660 | I>S | No |
ClinGen 1000Genomes |
|
|
rs1277608336 CA356681903 |
661 | N>D | No |
ClinGen gnomAD |
|
|
CA356681907 rs1369458933 |
661 | N>K | No |
ClinGen gnomAD |
|
|
CA356681911 rs1219504130 |
662 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA2885730 rs9654132 VAR_046342 |
662 | R>H | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs56412718 CA2885731 |
663 | P>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA356681926 rs1320891316 |
664 | Q>H | No |
ClinGen gnomAD |
|
|
rs1000681587 CA356681931 |
665 | S>I | No |
ClinGen TOPMed gnomAD |
|
|
RCV001301727 CA95809823 rs1000681587 |
665 | S>N | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
rs1258085323 CA356681935 |
666 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
CA356681936 rs1258085323 |
666 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA95809832 rs1027474626 |
667 | K>E | No |
ClinGen Ensembl |
|
| TCGA novel | 667 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA95809839 rs951936481 |
668 | R>K | No |
ClinGen Ensembl |
|
|
CA356681949 rs951936481 |
668 | R>T | No |
ClinGen Ensembl |
|
|
CA356681981 rs1578498650 |
673 | P>T | No |
ClinGen Ensembl |
|
|
CA2885733 rs760693725 |
674 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1578498654 CA356681987 |
674 | V>I | No |
ClinGen Ensembl |
|
|
CA2885739 rs149895631 |
678 | W>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA2885740 rs781126662 RCV001343644 |
680 | N>S | No |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
|
rs932024510 CA95814193 |
683 | H>R | No |
ClinGen gnomAD |
|
|
rs745341400 CA2885741 |
686 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA356682086 rs1165007847 |
687 | E>Q | No |
ClinGen gnomAD |
|
|
rs1405829681 CA356682101 |
689 | L>I | No |
ClinGen gnomAD |
|
|
rs1322703649 CA356682112 |
690 | S>L | No |
ClinGen gnomAD |
|
|
rs1578504385 CA356682135 |
693 | N>K | No |
ClinGen Ensembl |
|
|
RCV001206929 CA2885742 rs554146987 |
694 | A>T | No |
ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD |
|
|
CA356682141 rs1362467456 |
694 | A>V | No |
ClinGen TOPMed |
|
|
CA356682142 rs1401533745 |
695 | E>K | No |
ClinGen gnomAD |
|
|
rs1438760215 CA356682152 |
696 | S>A | No |
ClinGen TOPMed |
|
|
rs1298420227 CA356682154 |
696 | S>C | No |
ClinGen gnomAD |
|
|
CA356682172 rs1224621928 |
699 | S>L | No |
ClinGen gnomAD |
|
|
rs890573511 CA95814234 |
699 | S>T | No |
ClinGen Ensembl |
|
|
rs961842636 CA95814239 |
700 | T>A | No |
ClinGen TOPMed |
|
|
CA356682177 rs1285413893 |
700 | T>S | No |
ClinGen gnomAD |
|
|
rs971824954 CA95814241 |
702 | P>S | No |
ClinGen TOPMed |
|
|
CA2885744 rs144952478 |
704 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1228231249 RCV001229430 CA356682195 |
704 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ClinVar NCI-TCGA dbSNP gnomAD |
|
rs376760844 CA2885746 |
705 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA2885745 rs376760844 |
705 | R>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
RCV001319289 CA95814255 rs531713656 |
705 | R>H | No |
ClinGen ClinVar 1000Genomes dbSNP gnomAD |
|
|
rs376760844 CA356682198 |
705 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA356682206 rs1312363383 |
706 | S>N | No |
ClinGen gnomAD |
|
|
RCV001237482 rs930334304 CA95814257 |
707 | T>S | No |
ClinGen ClinVar TOPMed dbSNP |
|
|
rs1262747941 CA356682220 |
708 | I>M | No |
ClinGen gnomAD |
|
|
CA356682219 rs1217728031 |
708 | I>T | No |
ClinGen gnomAD |
|
|
CA356682215 rs1354706272 |
708 | I>V | No |
ClinGen TOPMed |
|
|
CA2885748 rs369707707 |
709 | Q>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1189733909 CA356682241 |
712 | K>E | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 712 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA356682265 rs1406567270 |
715 | N>D | No |
ClinGen TOPMed |
|
|
CA95814268 rs1027028687 |
715 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs773408776 CA95814278 |
716 | P>T | No |
ClinGen Ensembl |
|
|
CA356682281 rs1238099417 |
717 | D>E | No |
ClinGen gnomAD |
|
|
rs543928536 CA2885749 |
718 | D>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1420626069 CA356682293 |
719 | L>P | No |
ClinGen TOPMed |
|
|
rs565316336 CA2885750 RCV001049630 |
723 | I>F | No |
ClinGen ClinVar 1000Genomes ExAC dbSNP gnomAD |
|
|
CA356682320 rs1383212360 |
723 | I>N | No |
ClinGen gnomAD |
|
|
CA356682326 rs1578504612 |
724 | H>Y | No |
ClinGen Ensembl |
|
|
CA95814306 rs990926125 |
725 | E>K | No |
ClinGen TOPMed |
|
|
CA356682358 rs1376616127 |
728 | C>Y | No |
ClinGen TOPMed |
|
|
rs1421304899 CA356682362 |
729 | F>L | No |
ClinGen gnomAD |
|
|
rs372527757 CA2885751 |
730 | W>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA2885752 rs770971496 |
730 | W>S | No |
ClinGen ExAC gnomAD |
|
|
CA356682391 rs1041254036 |
732 | K>N | No |
ClinGen TOPMed gnomAD |
|
|
rs1335679249 CA356682387 |
732 | K>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1313568784 CA356682395 |
733 | S>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1448029725 CA356682394 |
733 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
CA356682411 rs1241366338 |
736 | T>A | No |
ClinGen gnomAD |
|
|
RCV001345302 CA356682415 rs1288449967 |
736 | T>I | No |
ClinGen ClinVar TOPMed dbSNP |
|
|
CA95814332 rs901369058 |
738 | T>N | No |
ClinGen TOPMed |
|
|
rs1285695169 CA356682424 |
738 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA356682430 rs1235443089 |
739 | D>H | No |
ClinGen TOPMed |
|
|
CA356682429 rs1235443089 |
739 | D>N | No |
ClinGen TOPMed |
|
|
CA356682438 rs1202359462 |
740 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1279501831 CA356682441 |
740 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA356682453 rs1441901710 |
742 | R>C | No |
ClinGen gnomAD |
|
|
rs1181772255 CA356682454 |
742 | R>H | No |
ClinGen gnomAD |
|
|
rs1430047323 CA356682461 |
743 | L>P | No |
ClinGen gnomAD |
|
|
CA356682467 rs1193581957 |
744 | L>P | No |
ClinGen gnomAD |
|
|
CA356682468 rs1441428754 |
745 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs1342830438 CA356682475 |
746 | R>* | No |
ClinGen TOPMed |
|
|
CA356682478 rs1179052199 |
746 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
CA356682476 rs1179052199 |
746 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA95814351 rs977890073 |
747 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs181892217 COSM255838 COSM255839 CA2885755 |
749 | R>C | Variant assessed as Somatic; 5.938e-05 impact. central_nervous_system [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA2885756 COSM3365612 rs186265781 COSM3365611 |
749 | R>H | kidney [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
| TCGA novel | 749 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs181892217 CA2885754 |
749 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs989420464 CA95814370 |
750 | K>R | No |
ClinGen gnomAD |
|
|
rs761624657 CA2885758 |
754 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs1001336589 CA95814392 |
754 | S>R | No |
ClinGen gnomAD |
|
|
rs1578504827 CA356682532 |
755 | D>G | No |
ClinGen Ensembl |
|
|
rs1169809027 CA356682528 |
755 | D>N | No |
ClinGen TOPMed |
|
|
rs921876192 CA95814394 |
756 | L>P | No |
ClinGen Ensembl |
|
|
CA95814395 rs1000646038 |
757 | A>P | No |
ClinGen TOPMed gnomAD |
|
|
CA356682542 rs1000646038 |
757 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
RCV001305511 rs767373613 CA2885759 |
759 | E>Q | No |
ClinGen ClinVar ExAC TOPMed dbSNP gnomAD |
|
|
CA356682564 rs1400389184 |
760 | L>R | No |
ClinGen gnomAD |
|
|
CA2885761 rs752511379 |
765 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2885762 rs779500614 |
766 | N>K | No |
ClinGen ExAC |
|
|
CA356682614 RCV001297460 rs1024204311 |
767 | K>E | No |
ClinGen ClinVar TOPMed dbSNP gnomAD |
|
|
CA95814467 rs1024204311 |
767 | K>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA356682624 rs1344500221 |
768 | V>E | No |
ClinGen gnomAD |
|
|
CA2885763 rs753501702 |
769 | F>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA2885765 rs778730054 |
770 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs529961646 CA2885766 |
771 | E>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA356682656 rs1417070852 |
773 | Q>R | No |
ClinGen gnomAD |
|
|
CA356682673 rs1200664167 |
775 | C>* | No |
ClinGen gnomAD |
|
|
rs986250718 CA95814482 |
775 | C>F | No |
ClinGen TOPMed |
|
|
CA356682688 rs1347940083 |
777 | D>V | No |
ClinGen gnomAD |
|
|
CA95814508 rs548088407 |
778 | V>I | No |
ClinGen 1000Genomes |
|
|
CA2885767 RCV001314494 rs772571231 |
779 | A>D | No |
ClinGen ClinVar ExAC dbSNP gnomAD |
|
|
CA95814530 rs752781889 |
781 | E>D | No |
ClinGen gnomAD |
No associated diseases with Q6ZMT9
3 regional properties for Q6ZMT9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Death domain | 682 - 763 | IPR000488 |
| domain | ZU5 domain | 167 - 301 | IPR000906-1 |
| domain | ZU5 domain | 302 - 483 | IPR000906-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHDECTPQQT | MSSIQDTKAA | DIAARGELNV | IETATVSPTN | GEESHYTNQV | QLEKNKTHMS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SALVEKENNT | SLNGRVLGQE | ESQNKMFPDN | AENEDDKQIE | HMTVENINGN | REETHGIIQT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TETEIQETSE | SPREEMTTSS | IICDISKKYI | NSTLPNDSEN | IKHKNNIMEK | EYLDVLSDVT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GPQVSCYITA | PSYVLQQLEC | RIINHMSSLI | VGDNEELVSN | VITIECSDKE | KRVPFPIGIA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IPFTARYRGN | YRDIMVKVCD | INLQSSYLNP | NSLEGMKGGY | KGTCASVKVY | KLGIFSVVSC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LKKESFTVTK | KGLALKSSMD | SRISLNYPPG | VFTSPVLVQL | KIQPVDPALV | AHLKAQQDTF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YSVQSTSPLI | HIQHPSTYPF | QKPVTLFLPC | SPYLDKNNLG | SEIDHKRRAS | ATINRITPSY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FNRTKIASIR | KPRKNASECL | KLLGFRSQDS | GWCGLDDVVK | TIQSGLVSVE | LYEHLERFIV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LHLSSTMDNS | HLVTFVKSLE | EAMLSTTACI | VLSHQKDNPH | RIAVLVVPSK | DLSQVLKDLH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LEGFGGPPEP | SRHFQVREGE | QLLLRFTGNI | FASSNGKDYG | KDYTLIFHLQ | RKPRLELQIK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EVDEFGNYSC | PHYKGTIVVY | KVPKGKIVPN | LNQSLVINEN | HSQLPICKLP | LKLPKHKKLI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NRPQSTKRVS | KDPVEALWDN | LLHWLAEELS | EENAESLSST | LPLRRSTIQL | IKLKNPDDLT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EQIHEFLCFW | KKSLPTFTDK | LRLLARHLRK | IGRSDLAEEL | KFKWENKVFT | EPQQCFDVAP |
| E |