Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6XXY0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6XXY0-F1 | Predicted | AlphaFoldDB |
No variants for Q6XXY0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6XXY0 | |||||
No associated diseases with Q6XXY0
1 regional properties for Q6XXY0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 53 - 400 | IPR017452 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| dendrite | A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled serotonin receptor activity | Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. |
10 GO annotations of biological process
| Name | Definition |
|---|---|
| adenylate cyclase-inhibiting serotonin receptor signaling pathway | An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process. |
| behavioral fear response | An acute behavioral change resulting from a perceived external threat. |
| exploration behavior | The specific behavior of an organism in response to a novel environment or stimulus. |
| regulation of behavior | Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. |
| regulation of dopamine metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. |
| regulation of hormone secretion | Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. |
| regulation of serotonin secretion | Any process that modulates the frequency, rate or extent of the regulated release of serotonin. |
| regulation of vasoconstriction | Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels. |
| serotonin metabolic process | The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. |
| serotonin receptor signaling pathway | The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGLSPGQGN | NTTSSEGPFG | TRGNATGISD | VTFSYQVITS | LLLGTLIFCA | VLGNACVVAA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IALERSLQNV | ANYLIGSLAV | TDLMVSVLVL | PMAALYQVLN | KWTLGQVTCD | LFIALDVLCC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TSSILHLCAI | ALDRYWAITD | PIDYVNKRTP | RRAAALISLT | WLIGFLISIP | PMLGWRTPED |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RSDPDACTIS | KDHGYTIYST | FGAFYIPLLL | MLVLYGRIFR | AARFRIRKTV | KKAERKGADA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RSGVSPAPQP | RKSVNGEPGG | REWRQGPGSK | AGGPLCTNGA | VRRGDDGAAL | EVIEVHRVGS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SKEHLPLPSE | AGAIPCAPAS | FEKKNERNAE | AKRKMALARE | RKTVKTLGII | MGTFILCWLP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FFIVALVLPF | CESSCHMPTL | LGAIINWLGY | SNSLLNPVIY | AYFNKDFQNA | FKKIVRCKFC |
| RRR |