Q6XMH7

PR
Gene name
MAP2
Protein name
Methionine aminopeptidase 2
Names
MAP 2, MetAP 2, Peptidase M
Species
Encephalitozoon intestinalis (strain ATCC 50506) (Microsporidian parasite) (Septata intestinalis)
KEGG Pathway
ein:Eint_100700
EC number
3.4.11.18: Aminopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

6-75 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6XMH7

Entry ID Method Resolution Chain Position Source
AF-Q6XMH7-F1 Predicted AlphaFoldDB

No variants for Q6XMH7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6XMH7

No associated diseases with Q6XMH7

2 regional properties for Q6XMH7

Type Name Position InterPro Accession
domain Peptidase M24 48 - 345 IPR000994
binding_site Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site 125 - 141 IPR018349

Functions

Description
EC Number 3.4.11.18 Aminopeptidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloaminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

2 GO annotations of biological process

Name Definition
protein initiator methionine removal The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKFILIDQAP ELPIEFLPKG DCYRKGRLFG PKGEEIENTT DCDLLQDARR AAEAHRRARY
70 80 90 100 110 120
KVQSIIRPGI TLLEIVRSIE DSTRTLLEGE RNNGIGFPAG MSMNSCAAHY TVNPGEEDIV
130 140 150 160 170 180
LKEDDVLKVD FGTHSNGRIM DSAFTVAFQE NLQPLLMAAR EGTETGIRSL GIDARVCDIG
190 200 210 220 230 240
RDINEVITSY EVEIEGKTWP IRPVSDLHGH SISQFKIHGG ISIPAVNNRD TTRIKGDTFY
250 260 270 280 290 300
AVETFATTGK GFINDRSPCS HFMLNVHKSR KLFNKDLIKV YEFVKSSFGT LPFSPRHLDH
310 320 330 340 350
YNLVEGGSLK SVNLLTMMGL FTPYPPLNDI DGSKVAQFEH TVYLSENGKE ILTRGDDY