Q6WNR0
Gene name |
CYP81E7 |
Protein name |
Isoflavone 2'-hydroxylase |
Names |
4'-methoxyisoflavone 2'-hydroxylase, Cytochrome P450 81E7 |
Species |
Medicago truncatula (Barrel medic) (Medicago tribuloides) |
KEGG Pathway |
mtr:MTR_4g094775 |
EC number |
1.14.14.89: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6WNR0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6WNR0-F1 | Predicted | AlphaFoldDB |
No variants for Q6WNR0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6WNR0 | |||||
No associated diseases with Q6WNR0
1 regional properties for Q6WNR0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 429 - 438 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.89 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4'-methoxyisoflavone 2'-hydroxylase activity | Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGILSYLCYS | LFYLSIFFII | RLLFQSRKFK | NLPPGPTSLP | IIGNLHHLKR | PLNRTFKALT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKYGNVISLW | FGSRLVVVVS | SLSEFQECFT | KNDVVLANRP | RFLSGKYIFY | NYTTLGSTSY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GEHWRNLRRI | TSLDVLSNHR | INNFAPIRRD | ETQRLIKKLA | EDSSTKFAEV | ELTFRFFDMT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FNNIMRMISG | KRYYGDDCDI | SEVQEASQFR | DMVSELLQLS | GANNKTDFMP | LLKFLDFENL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EKRVKRIGEK | NDVFLSGLLQ | EQRSKKERTN | TMIDHLLNMQ | ESQPEYYTDT | IIKGLCLAML |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAGTDSSAVT | LEWTMSNILN | YPEVLKKVRD | EVDTHVGQDR | LVDESDLPKL | TYLRNVIYET |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRLYTPAPLL | LPHSTADECI | MGGYKVPRDT | IVLINAWAIH | RDPETWSEAT | TFKPERFDKK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GELEKMIAFG | MGRRACPGEG | LALRAISMTL | ALLVQCFDWK | RINDEKIDMS | ERDGFTMTKL |
| 490 | |||||
| LPLKAMCKTR | PVVNKVFK |