Q6URB0

PR
Gene name
CCP1 (CNAG_01138)
Protein name
Cytochrome c peroxidase, mitochondrial
Names
CCP
Species
Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
KEGG Pathway
EC number
1.11.1.5: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6URB0

Entry ID Method Resolution Chain Position Source
AF-Q6URB0-F1 Predicted AlphaFoldDB

No variants for Q6URB0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6URB0

No associated diseases with Q6URB0

3 regional properties for Q6URB0

Type Name Position InterPro Accession
domain Haem peroxidase 117 - 377 IPR002016
binding_site Peroxidases heam-ligand binding site 253 - 263 IPR019793
active_site Peroxidase, active site 129 - 140 IPR019794

Functions

Description
EC Number 1.11.1.5 Peroxidases
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope.
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

3 GO annotations of molecular function

Name Definition
cytochrome-c peroxidase activity Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
cellular response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFRAPNLIR STVGRRAGQT LNLRSQVIRR RFATEGGPEI TKPSAPRSSN TGYIFAGLGV
70 80 90 100 110 120
AAVGAAYYFY GTGRTEHDST NKADTVVREA VATVEAKTGL RRGKDEYQKV YNRIAETLDK
130 140 150 160 170 180
EGYDDGSLAP VLLRLAWHAS GTYSKADGTG GSNFATMRFK PEAEHSANNG LHVAREHMEK
190 200 210 220 230 240
IKQEFPWISY GDLWTLGGVC AIQESGGPTI PWRPGRIDGY AAQVTPDGRL PDATQAQDHL
250 260 270 280 290 300
RFIFNRMGFN DQEIVALSGA HAMGRCHPNR SGFDGPWTFS PVTFSNQYFA LLRDEPWQWK
310 320 330 340 350 360
KWTGPAQFED KKTKTLMMLP TDMALVKDKS FKKYVDIYAD NEEKFFSDFA KAFSKLIELG
370
VPERQWAGEP WTMATSD