Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6TXG9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6TXG9-F1 | Predicted | AlphaFoldDB |
1 variants for Q6TXG9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3319250881 | 45 | T>I | No | EVA |
No associated diseases with Q6TXG9
No regional properties for Q6TXG9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6TXG9 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| Swi5-Sfr1 complex | A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces). |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| nuclear receptor coactivator activity | A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to estrogen stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. |
| double-strand break repair via homologous recombination | The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASAPSDIPE | NAFRLAKASG | RCQSMMSQMK | DETKCMGAVF | SGYPTALWLE | YEVSPQPMSG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TLKERLKKAR | ASSQPFCSVV | KRIKVENEEN | DQTLSEPGES | SKEENCSKAQ | ESLENKDNEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EKESSEDKNT | SESKSLDTGS | SSVLQKDSTE | KTIKQTLKEE | KAKLTRQVQE | KEDLLRRLKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKMYRIKNDV | TELEDLIKKW | RRCGQRLLCE | LQSIMSEDED | EKLTLTELID | YYGIDDKLLH |
| 250 | |||||
| YNRTEEEFTG | V |