Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6T5K2

Entry ID Method Resolution Chain Position Source
AF-Q6T5K2-F1 Predicted AlphaFoldDB

No variants for Q6T5K2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6T5K2

No associated diseases with Q6T5K2

1 regional properties for Q6T5K2

Type Name Position InterPro Accession
conserved_site ELO family, conserved site 137 - 145 IPR030457

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

2 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
regulation of intracellular signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLLSTWTPGC FQGNKILLRS LITWYYLEFM PKLRPFYFLF YLTLPSCATD SPPISDKSSS
70 80 90 100 110 120
IFLPLAQQQQ LVHWMMPPRF RCQDYLLPLL LALSPAAAAA REVEYHHCHC DGGGGGGGGG
130 140 150 160 170 180
LWSMDSIFRR QKVSDLLIAA AYFSIPLEIL YFVAGLRHLL PFRWVLVQFG AFIVLCGLTH
190 200 210 220 230 240
LLTAFTYEPH PFMVVLLLTT AKFLTALVSF LTAITLLTLI PQLLRVKVRE SLLWLKAREL
250 260 270 280 290 300
DREVVLMKRQ EEASWHVRML THEIRKSLDR HTVLYTTLIE LSLVLGLTNC AVWMPAAGEM
310 320 330 340 350 360
CLTHELRRDG GGEDGVVGVD DADVVEVRGS DGVKLLGPDS VLAAASGGKE EGTGAVAAIR
370 380 390 400 410 420
MPMLKVSDFK GGTPEVIQTS YAVLVLVPPA GKSWGRHEME IVEVVAGQVA VALSHATLLE
430 440 450 460 470 480
ESRAMRDRLA EQNRELLQAR RDALMANEAR QAFQGVMSQG MRRPIHSILG LVSMVQEEAL
490 500 510 520 530 540
APEQRLVVDT MARTATVVST LVNDVMEMSA DSRERFPLET RPFHLHAMIR DAACVARCLC
550 560 570 580 590 600
DFRGFGFAVH VENALPDLVV GDERRIFHVL LHMVGNLIGR TEPGHVTLRV RAADDDVLDD
610 620 630 640 650 660
RLGQRWDPRW PSYSTGYSSV KFVIGVKRQQ NGDAGSPLSR RPSGKGIDLR LSFSMCRKLV
670 680 690 700 710 720
QMMQGNIWAI NDPQGLPESM TLVLRFQLQS PLTSSSLGGS FEQKHSSPSC QIAGLKVLLI
730 740 750 760 770 780
DDDDDINLVV ARKLLEKLGC VVSSPPSGSG FLSSVGSSAA AFQLVMVNLE MKRVKALDVA
790 800 810 820 830
TRISQYRSGR WPIVMAMASD QKAWEKCAQS GINGILKKPV ILQELKDELA RILQST