Q6SW29
Gene name |
UL122 |
Protein name |
Viral transcription factor IE2 |
Names |
IE2, Protein UL122 |
Species |
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5) |
KEGG Pathway |
vg:3077563 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for Q6SW29
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for Q6SW29
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6SW29 | |||||
No associated diseases with Q6SW29
1 regional properties for Q6SW29
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Herpesvirus intermediate/early protein 2/3 | 383 - 543 | IPR005028 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| host cell nucleus | A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| metal ion binding | Binding to a metal ion. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated viral transcription | A transcription process that uses a viral DNA as a template. |
| modulation by virus of host G0/G1 transition checkpoint | Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint. |
| modulation by virus of host G1/S transition checkpoint | Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESSAKRKMD | PDNPDEGPSS | KVPRPETPVT | KATTFLQTML | RKEVNSQLSL | GDPLFPELAE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ESLKTFEQVT | EDCNENPEKD | VLTELGDILA | QAVNHAGIDS | SSTGPTLTTH | SCSVSSAPLN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KPTPTSVAVT | NTPLPGASAT | PELSPRKKPR | KTTRPFKVII | KPPVPPAPIM | LPLIKQEDIK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PEPDFTIQYR | NKIIDTAGCI | VISDSEEEQG | EEVETRGATA | SSPSTGSGTP | RVTSPTHPLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QMNHPPLPDP | LGRPDEDSSS | SSSSSCSSAS | DSESESEEMK | CSSGGGASVT | SSHHGRGGFG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GAASSSLLSC | GHQSSGGAST | GPRKKKSKRI | SELDNEKVRN | IMKDKNTPFC | TPNVQTRRGR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VKIDEVSRMF | RHTNRSLEYK | NLPFMIPSMH | QVLEEAIKVC | KTMQVNNKGI | QIIYTRNHEV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KNEVDQVRCR | LGSMCNLALS | TPFLMEHTMP | VTHPPDVAQR | TADACNDGVK | AVWNLKELHT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HQLCPRSSDY | RNMIIHAATP | VDLLGALNLC | LPLMQKFPKQ | VMVRIFSTNQ | GGFMLPIYET |
| 550 | 560 | 570 | |||
| AAKAYAVGQF | EKPTETPPED | LDTLSLAIEA | AIQDLRNKSQ |