Q6RWA9

PR
Gene name
Protein name
Sodium/potassium-transporting ATPase subunit alpha
Names
Na(+)/K(+) ATPase alpha subunit, Sodium pump subunit alpha, TNaK1-alpha
Species
Taenia solium (Pork tapeworm)
KEGG Pathway
EC number
7.2.2.13: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6RWA9

Entry ID Method Resolution Chain Position Source
AF-Q6RWA9-F1 Predicted AlphaFoldDB

No variants for Q6RWA9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6RWA9

No associated diseases with Q6RWA9

3 regional properties for Q6RWA9

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 45 - 55 IPR023409-1
conserved_site 14-3-3 protein, conserved site 217 - 236 IPR023409-2
domain 14-3-3 domain 5 - 249 IPR023410

Functions

Description
EC Number 7.2.2.13 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
P-type sodium:potassium-exchanging transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGKSRGDKYR DATDGKKDAK KDLNELKQEL AMDEHQISLD ELYARLGTNP DTGLTSEQAK
70 80 90 100 110 120
TRLDRDGPNA LTPPKTTPEW VKFCKNMFGG FSLLLWIGAV LCFIAHGIPC WCAGEPYLYD
130 140 150 160 170 180
NLYLGIVLAA VVVITGCFSY YQESKSSKIM ESFAKLVPQY AVVIRGGQRI DAPAEALVVG
190 200 210 220 230 240
DIIDVKFGDR VPADIRVIKA SSFKVDNSAL TGESEPQTRT AEYTNENPLE TKNLAFFSTN
250 260 270 280 290 300
AVEGTCRGVV VATGDRTVMG RIANLASGLE MGATPIAREI AHFIHIITGV AVFLGVTFFI
310 320 330 340 350 360
IAFILGYYWL DAVIFLIGII VANVPEGLLA TVTVCLTLTA KRMASKNCLV KNLEAVETLG
370 380 390 400 410 420
STSTICSDKT GTLTQNRMTV AHMWFDNKIF EADTSDDQST ANYSRASSTW MALSRIAMLC
430 440 450 460 470 480
NRAEFKPGEE TNPVLKRECN GDASESALLK CVGLSIGGVT GYRTDKPKVA EIPFNSTNKY
490 500 510 520 530 540
QVSVHQTDDG DERYLVVMKG APERILDRCS TVLMEGQELH MDDQWRESFN NAYLELGGIG
550 560 570 580 590 600
ERVLGFCDLR LPADKFPRGF KFDIDEPNFP IEGMPFVGLM SMIDPPRAAV PDAVSKCRSA
610 620 630 640 650 660
GIKVVMVTGD HPITAKAIAK GVGIISDGNK TVEDIAAERG VPVSQVNPRE ASACVVHGSD
670 680 690 700 710 720
LRDMTPAQID EILENHSEIV FARTSPQQKL IIVEGIQRMG AIVAVTGDGV NDSPALKKAD
730 740 750 760 770 780
IGVAMGITGS DVSKQAADMI LLDDNFASIV TGVEEGRIIF DNLKKSIAYT LTSNIPEITP
790 800 810 820 830 840
FLIFILADVP LPLGTITILC IDLGTDMVPA ISLAYEEAED IMKRMPRDPF RDKLVNERLI
850 860 870 880 890 900
SMAYGQIGMI QASGGFFVYF VIMAENGFWP SRLLGLRKQW DSPAINDVAD SYGQEWTYTQ
910 920 930 940 950 960
RKRLEYTCHT AFFASIVIVQ WTDLLICKTR KNSIYQQGMW NHHLTFGLFF ETTLAIFLSY
970 980 990 1000 1010
CPGLEHGLRM MPLRWTWWLP VLPFSVSIFI FDEVRKKFLR TLPPGNWVER ETNY