Q6NXA9

PR
Gene name
ubxn1 (saks1, zgc:77531)
Protein name
UBX domain-containing protein 1
Names
SAPK substrate protein 1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:322073
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

6-245 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6NXA9

Entry ID Method Resolution Chain Position Source
AF-Q6NXA9-F1 Predicted AlphaFoldDB

No variants for Q6NXA9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6NXA9

No associated diseases with Q6NXA9

3 regional properties for Q6NXA9

Type Name Position InterPro Accession
domain UBX domain 210 - 293 IPR001012
domain Ubiquitin-associated domain 1 - 42 IPR015940
domain UBXN1, UBA domain 5 - 45 IPR041923

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
K48-linked polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein.
K6-linked polyubiquitin modification-dependent protein binding Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.

3 GO annotations of biological process

Name Definition
negative regulation of proteasomal ubiquitin-dependent protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
negative regulation of protein K48-linked deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination.
negative regulation of protein ubiquitination Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADCTTLDSL LEMGFGRNRA EKAVAHTGNQ GIERAMDWLM EHENDPDIDE PYVPPAGNTL
70 80 90 100 110 120
GPAEEQSQSP TEIPESIEDT EEGNARQPMT EEERKEQVKR LEDLMKARQE ERRERERQEG
130 140 150 160 170 180
IEREKQRRKQ GQELLQVRQK LQEDEMKKLA DQRRKEKMED RLAKQRVKDK IARDREERAQ
190 200 210 220 230 240
KFGGGSSSTG LSSPPAEAPA LSPPENQGAP PAKKDYDDCR IQVRLLDGTT LSTVFKAQEP
250 260 270 280 290
LAAVRVYVQM NGANGQDFNL ITPYPRRVYT DLDMEKPLRE LGLVPSAVLV VTKK