Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6NTY8

Entry ID Method Resolution Chain Position Source
AF-Q6NTY8-F1 Predicted AlphaFoldDB

No variants for Q6NTY8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6NTY8

No associated diseases with Q6NTY8

1 regional properties for Q6NTY8

Type Name Position InterPro Accession
domain Rhodanese-like domain 168 - 274 IPR001763

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
  • Cell projection, cilium
  • Cytoplasm, cytoskeleton, cilium basal body
  • Localizes mainly to the cilium basal body and in primary cilia
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
centriole A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
ciliary basal body A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
cilium A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cilium assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
protein polyglutamylation The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAKRSIGDS EILKKRIPQN QKYEHIKTRL DTGNSMTKYL ERIEDIKRNY RYKKDELFKR
70 80 90 100 110 120
IKVTTFAQLV LQVASVTEER ESGEMTTDEL QRLEDNSSVI SDTEFLTDRP NGKGSPANES
130 140 150 160 170 180
NSPIQFIDSE RGEELIQTSR STLQSVISGV GELDLGNQAD IKKESLPSSS ALDKPYEDCP
190 200 210 220 230 240
FLLLDVRDRD SYDQCHIVGA RNYPIAMLSR TMNPFTPEIL EYRNAHGKII ILYDEDERVA
250 260 270 280 290 300
SQAASTMCER GFENLFMLSG GLKVISQRFP QGLTTGSFPI TCLAPPTQTK SALKRTPKDP
310 320 330 340 350 360
IIPAENKWRF SSQDLEMIEN HLENVLMSTS TPSRLRMDSR NSKVPSSASS ARSQSSTSSH
SKPWK