Q6NS60

PR
Gene name
Fbxo41 (D6Ertd538e, Kiaa1940)
Protein name
F-box only protein 41
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:330369
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

358-521 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6NS60

Entry ID Method Resolution Chain Position Source
AF-Q6NS60-F1 Predicted AlphaFoldDB

32 variants for Q6NS60

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3396966028 49 D>G No EVA
rs3396997233 115 L>V No EVA
rs265714394 231 Q>R No EVA
rs3388834334 237 A>V No EVA
rs3388836292 275 D>E No EVA
rs3388840576 275 D>V No EVA
rs3396583636 278 V>A No EVA
rs3388823033 297 R>C No EVA
rs3388836593 321 L>Q No EVA
rs3388847892 375 M>I No EVA
rs3388847907 385 P>S No EVA
rs3388827363 412 S>L No EVA
rs3388836585 477 T>N No EVA
rs3388836364 492 T>S No EVA
rs3388841523 493 E>V No EVA
rs3388838022 556 F>I No EVA
rs3388819561 570 A>T No EVA
rs3388836301 572 E>D No EVA
rs3388842705 586 V>L No EVA
rs49954911 589 R>S No EVA
rs3388834353 597 V>F No EVA
rs3388841991 609 C>Y No EVA
rs3388842011 625 R>Q No EVA
rs3388840809 634 Y>* No EVA
rs3396745241 640 G>S No EVA
rs3388836349 647 E>Q No EVA
rs3388836612 660 L>V No EVA
rs3388807137 713 S>F No EVA
rs3388840732 727 R>G No EVA
rs3388838083 741 P>H No EVA
rs3388842050 746 L>Q No EVA
rs3388841581 760 S>P No EVA

No associated diseases with Q6NS60

5 regional properties for Q6NS60

Type Name Position InterPro Accession
domain FCH domain 16 - 105 IPR001060
domain SH3 domain 466 - 527 IPR001452-1
domain SH3 domain 544 - 607 IPR001452-2
domain F-BAR domain 12 - 280 IPR031160
domain FCHSD, SH3 domain 1 468 - 524 IPR035460

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8TF61 FBXO41 F-box only protein 41 Homo sapiens (Human) PR
10 20 30 40 50 60
MASLDLPYRC PRCGEHKRFR SLSSLRAHLE YSHTYETLYI LSKTNSICDG AAAAAAAAAA
70 80 90 100 110 120
ASGFPLAPEP AALLAVPGAR REVFESTSFQ GKEQATGPSP AGPHLLHHHH HHAPLAHFPA
130 140 150 160 170 180
DLVPASLPCE ELAEPGLVPA ARYALREIEI PLGELFARKS VASSACSTPP PGPGPGPCSG
190 200 210 220 230 240
PSSASPASPS PADVAYEEGL ARLKIRALEK LEVDRRLERL SEEVEQKIAG QVGRLQAELE
250 260 270 280 290 300
RKAAELETAR QESARLGREK EELEERASEL SRQVDVSVEL LASLKQDLVH KEQELSRKQQ
310 320 330 340 350 360
EVVQIDQFLK ETAAREASAK LRLQQFIEEL LERADRAERQ LQVISSSCGS TPSASLGRGG
370 380 390 400 410 420
GGSASGPGVR GPGRMREHHA GSAVPSTYAV SRHGSSPSTG ASSRVPAASQ SSGCYDSDSL
430 440 450 460 470 480
ELPRPEEGPS EDSGPGGLGS RAQATNGGSE RSQAPRSSGL RRQAIQNWQR RPRRHSTEGE
490 500 510 520 530 540
EGDVSDVGSR TTESEAEGPS DVPRPGPAVA GPLNSCRLSA RPEGGSGRGR RVERGSPSRS
550 560 570 580 590 600
NEVISPEILK MRAALFCIFT YLDTRTLLHA AEVCRDWRFV ARHPAVWTRV LLENARVCSK
610 620 630 640 650 660
FLAMLAQWCT QAHSLTLQNL KPRQRGKKES KEEYARSTRG CLEAGLESLL KAAGGNLLIL
670 680 690 700 710 720
RISHCPNILT DRSLWLASCY CRALQAVTYR SATDPVGHEV IWALGAGCRD IVSLQVAPLH
730 740 750 760 770 780
PCQQPTRFSN RCLQMIGRCW PHLRALGVGG AGCGVQGLAS LARNCMRLQV LELDHVSEIT
790 800 810 820 830 840
QEVAAEVCRE GLKGLEMLVL TATPVTPKAL LHFNSICRNL KSIVVQIGIA DYFKEPSSPE
850 860 870
AQKLFEDMVT KLQALRRRPG FSKILHIKVE GGC