Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6NRY2

Entry ID Method Resolution Chain Position Source
AF-Q6NRY2-F1 Predicted AlphaFoldDB

No variants for Q6NRY2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6NRY2

No associated diseases with Q6NRY2

6 regional properties for Q6NRY2

Type Name Position InterPro Accession
domain Nrap protein domain 1 178 - 318 IPR035082
domain Nrap protein, domain 2 324 - 462 IPR035367
domain Nrap protein, domain 3 468 - 627 IPR035368
domain Nrap protein, domain 4 648 - 845 IPR035369
domain Nrap protein, domain 5 847 - 1002 IPR035370
domain Nrap protein, domain 6 1004 - 1137 IPR035371

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Chromosome
  • Localizes to condensed chromosomes in mitosis
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQKKRSRAGA AEQEAASDDG EMSDSSDKME VSQNKGKSGI KRAPEADDVL RPVKLSKSDL
70 80 90 100 110 120
YKPPTNDELN RLKETENLFH TNLLRMQIEE LLQEVKLKEK RRKTIDGFLH EINALLGTIP
130 140 150 160 170 180
ETPKTDLTDQ SWLSSSIKVP FLQVPYQVKG KFSFLPPSSI KVVGSYLLGT CIKPEINVDL
190 200 210 220 230 240
AVTMPQEILQ VKDNLNQRYS RKRALYLAHI ASHLTDNKLF SSVKFTYMNS NHLKPILLLR
250 260 270 280 290 300
PQGKDEKLVT VRIHICPPPG FFKLSRLYPN KNNVRTSWYT EQQTETEGVC DPPTPYYNNT
310 320 330 340 350 360
ILSDLTLEHH LHHLTNCATD FPGMKDAIAL LKVWLHQRQL DKGFGCFNGF LASMLISYLL
370 380 390 400 410 420
SKNKINKVMS GYQVLRNTLQ FLATTDLTVN GITMATCSDS SLPSLPDFHE AFQVVFVDPM
430 440 450 460 470 480
GVVNLCADMT ASKYRQIQFE ASESLKVLDD TNVNGFHLLL MVPKPFVRTF DHVFHLTNVA
490 500 510 520 530 540
KLQGTCKKMK LLNQLIDRGG DYLATALPYL LSVLSKGLGP RVSLLSHTLT HKPEWNVGEE
550 560 570 580 590 600
PAKHKDSGLV TVGLLLDPEL YTNVLDKGPA ADSSEALDFR AFWGEKSELR RFQDGSICEA
610 620 630 640 650 660
VVWTGGSLYD KRKVPELIVK YLLELHANIP ESCINYTGNA LDCVLSRGRE TSTEEEKMVS
670 680 690 700 710 720
IIQSYDDLSR KLWNLNDLPL TITSVQGTHP CLRYTDVFPP LPVKPDWSSY HLLREKKCLI
730 740 750 760 770 780
PNPEKPCPAY VSPVKVICHM EGSGKWPQDK DAIKRLKAAF QIRLSELLSS QHQLLCNPSA
790 800 810 820 830 840
THTDVYKDGY VFRVQVAYHR EPQYMKEFVT PEGMLKYQDT EESMQLEMET NHLPHLSSTL
850 860 870 880 890 900
HGLHQQHPAF GGTSRLAKRW IQSQLLGDSF SEECLDLLVA HLFLHPAPYS PPSSALVGFL
910 920 930 940 950 960
RFLHLVATFD WKNSPLIVNL NGELKGSEYT EIQNDFISAR AQLPVMFIAT PKDKKDSVWT
970 980 990 1000 1010 1020
KNQPTAQMLQ RLIVLCLESL RALEQQLMDP RGNHDYKMIF RPPLDLYDVL IRLNPKQISR
1030 1040 1050 1060 1070 1080
HREAVDQPAK SFFRGMLKEG AQVKDLMFPV VGYDPIQLFL QELREAYGEF ALFFHDLHGG
1090 1100 1110 1120 1130 1140
DVIGVLWKPS SFEPQPFKTT NVKGRQMDGK SDKALLVPNA EAFVEDLEIL GEGLVAGVEA
QTERWNI