Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6NM25

Entry ID Method Resolution Chain Position Source
AF-Q6NM25-F1 Predicted AlphaFoldDB

49 variants for Q6NM25

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06242011 7 V>L No 1000Genomes
ENSVATH02445946 12 E>D No 1000Genomes
tmp_3_16956754_T_C 16 K>R No 1000Genomes
ENSVATH06242010 18 W>R No 1000Genomes
ENSVATH02445945 21 V>I No 1000Genomes
ENSVATH12554394 22 F>S No 1000Genomes
ENSVATH06242009 29 L>F No 1000Genomes
ENSVATH06242008 29 L>P No 1000Genomes
ENSVATH02445937 50 K>R No 1000Genomes
tmp_3_16956538_C_A 51 E>D No 1000Genomes
tmp_3_16956516_G_T 59 L>I No 1000Genomes
ENSVATH06241999 73 A>S No 1000Genomes
tmp_3_16956364_A_C 81 V>G No 1000Genomes
tmp_3_16956355_G_A 84 P>L No 1000Genomes
tmp_3_16956340_T_C 89 Y>C No 1000Genomes
tmp_3_16956332_A_T 92 C>S No 1000Genomes
ENSVATH12554389 136 M>V No 1000Genomes
ENSVATH14378618 139 K>N No 1000Genomes
ENSVATH02445930 141 R>K No 1000Genomes
tmp_3_16956090_C_G 142 G>A No 1000Genomes
ENSVATH02445929 142 G>R No 1000Genomes
ENSVATH12554388 145 Y>C No 1000Genomes
ENSVATH02445928 153 L>F No 1000Genomes
tmp_3_16956037_G_T 160 L>I No 1000Genomes
tmp_3_16955934_C_T 164 G>E No 1000Genomes
ENSVATH12554386 166 D>E No 1000Genomes
tmp_3_16955909_C_A 172 K>N No 1000Genomes
tmp_3_16955895_G_T 177 T>N No 1000Genomes
tmp_3_16955675_T_C 216 T>A No 1000Genomes
ENSVATH12554367 222 I>F No 1000Genomes
ENSVATH06241978 234 L>I No 1000Genomes
ENSVATH06241977 239 D>E No 1000Genomes
tmp_3_16955257_G_C 243 R>G No 1000Genomes
ENSVATH00401967 253 L>M No 1000Genomes
tmp_3_16954935_C_T 290 M>I No 1000Genomes
ENSVATH00401965 303 E>D No 1000Genomes
ENSVATH06241968 306 I>M No 1000Genomes
tmp_3_16954777_C_A 313 G>V No 1000Genomes
tmp_3_16954769_A_T 316 Y>N No 1000Genomes
ENSVATH02445898 320 F>L No 1000Genomes
tmp_3_16954757_A_C 320 F>V No 1000Genomes
ENSVATH02445897 321 V>L No 1000Genomes
ENSVATH02445897 321 V>M No 1000Genomes
ENSVATH06241966 328 P>L No 1000Genomes
ENSVATH00401962 329 P>Q No 1000Genomes
tmp_3_16954726_G_A 330 A>V No 1000Genomes
ENSVATH00401961 332 Q>E No 1000Genomes
tmp_3_16954715_G_T 334 L>I No 1000Genomes
ENSVATH14378577 340 A>V No 1000Genomes

No associated diseases with Q6NM25

No regional properties for Q6NM25

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6NM25

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of Golgi membrane The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6NMB6 UTR5B UDP-galactose/UDP-glucose transporter 5B Arabidopsis thaliana (Mouse-ear cress) PR
Q9LDX3 UTR4 UDP-galactose/UDP-glucose transporter 4 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAEPDSVNEA KEKKKKLWKA VFAISGIMLT LVIYGLLQEK IMRVPYGLKK EYFKHSLFLV
70 80 90 100 110 120
FCNRLTTSAV SAAALLASKK VLDPVAPVYK YCLISVTNIL TTTCQYEALK YVSFPVQTLA
130 140 150 160 170 180
KCAKMIPVMV WGTLIMQKKY RGFDYLVAFL VTLGCSVFIL FPAGDDISPY NKGRENTVWG
190 200 210 220 230 240
VSLMVGYLGF DGFTSTFQDK LFKGYNMEIH NQIFYTTICS SILSFTGLIL QGHLLPAVDF
250 260 270 280 290 300
VSRHRDCLFD IALLSTVATA SQFFISYTIR TFGALTFAAI MTTRQLASIM LSCIWFSHPL
310 320 330 340
SWEQCIGSVI VFGSLYAKTF VKKKSEKPPA AQELPRDEEA QPLKGNP