Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6NLW5

Entry ID Method Resolution Chain Position Source
AF-Q6NLW5-F1 Predicted AlphaFoldDB

21 variants for Q6NLW5

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH07374469 9 S>I No 1000Genomes
ENSVATH07374470 21 H>Q No 1000Genomes
ENSVATH12642341 48 M>L No 1000Genomes
ENSVATH12642342 58 A>T No 1000Genomes
tmp_5_19760115_C_G 60 S>R No 1000Genomes
ENSVATH07374475 67 T>I No 1000Genomes
tmp_5_19760241_G_T 73 R>M No 1000Genomes
tmp_5_19760252_G_A 77 V>M No 1000Genomes
ENSVATH12642369 88 R>C No 1000Genomes
tmp_5_19760759_A_T 131 I>L No 1000Genomes
tmp_5_19760908_G_A 155 A>T No 1000Genomes
tmp_5_19760927_C_T 161 A>V No 1000Genomes
tmp_5_19760929_G_A 162 E>K No 1000Genomes
ENSVATH12642393 173 G>S No 1000Genomes
ENSVATH14613549 188 P>S No 1000Genomes
tmp_5_19761194_G_A 194 R>K No 1000Genomes
ENSVATH07374504 196 V>I No 1000Genomes
ENSVATH07374504 196 V>L No 1000Genomes
tmp_5_19761220_T_C 203 S>P No 1000Genomes
ENSVATH12642427 222 L>V No 1000Genomes
ENSVATH14613550 296 M>L No 1000Genomes

No associated diseases with Q6NLW5

No regional properties for Q6NLW5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6NLW5

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
female meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
male meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
pollen development The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
response to X-ray Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDYGDDDRSS SWNWQVDNYN HQPQSHFSDV PDCTMTEVTL NQEDHSYMFD DENTPVKACS
70 80 90 100 110 120
ELGYHVTTED TNRKMEVHSE TRSALKRRRM LQFEDQPETS LFSSESFSAI LKSSARDDTF
130 140 150 160 170 180
DELLPEGSQL IEGFSEDASA SSFEGLDLYA EEWYADCLND AETPMLPDDL NFGSPDVQVD
190 200 210 220 230 240
ISEYLNVPPE TETREVQRPV TRSSPNVIFK GRKSFSRPVS KLPSSIIYPF AFIKPCGVHG
250 260 270 280 290
GMTLKDINQK IRNPPAKPKA HIEEPAVIQT SAFSGKPVVG KTKIRTEGGK GSITIMRTRG