Q6N4S0

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
KEGG Pathway
rpa:RPA3267
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1347-1402 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6N4S0

Entry ID Method Resolution Chain Position Source
AF-Q6N4S0-F1 Predicted AlphaFoldDB

No variants for Q6N4S0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6N4S0

No associated diseases with Q6N4S0

6 regional properties for Q6N4S0

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 348 - 489 IPR000722
domain RNA polymerase, N-terminal 239 - 518 IPR006592
domain RNA polymerase Rpb1, domain 3 493 - 646 IPR007066
domain RNA polymerase Rpb1, domain 1 20 - 346 IPR007080
domain RNA polymerase Rpb1, domain 5 764 - 1311 IPR007081
domain RNA polymerase Rpb1, domain 4 675 - 761 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAMNQEIMNL FNPTTPAQVF DQIRISIASP EKILSWSYGE IKKPETINYR TFKPERDGLF
70 80 90 100 110 120
CARIFGPIKD YECLCGKYKR MKYKGIICEK CSVEVTLSRV RRERMGHIEL AAPVAHIWFL
130 140 150 160 170 180
KSLPSRIGQL LDMTLKDLER ILYFEYYVVL EPGLTDLKER QLLSEEEYLR AQDQYGQDSF
190 200 210 220 230 240
TAMIGAEAIR ELLKGLELEK IDAQLRAEMA ETDSDIKHKK LAKRLKIVEA FRYSGNKPEW
250 260 270 280 290 300
MILTVVPVIP PDLRPLVPLD GGRFATSDLN DLYRRVINRN NRLKRLMELR APDIIIRNEK
310 320 330 340 350 360
RMLQEAVDAL FDNGRRGRVI TGANKRPLKS LADMLKGKQG RFRQNLLGKR VDYSGRSVIV
370 380 390 400 410 420
VGPELKLHQC GLPKKMALEL FKPFIYSRLD AKGLSTTVKQ AKKLVEKERP EVWDILDEVI
430 440 450 460 470 480
REHPVLLNRA PTLHRLGIQA FEPVLIEGKA IQLHPLVCSA FNADFDGDQM AVHVPLSLEA
490 500 510 520 530 540
QLEARVLMMS TNNILHPANG QPIIVPSQDI VLGLYYLSIM REGLPGEGKV FADLAELEHA
550 560 570 580 590 600
LYSKVIHLHT KIKYRWHWVN EEGENTVRLL ETTAGRILLG QVLPKSPKLP FDVINKLMTK
610 620 630 640 650 660
REISGVIDQV YRHCGQKETV IFCDRIMALG FFNAFKAGIS FGKDDMVVPG SKWKIVDSTR
670 680 690 700 710 720
TLAKDFEQQY NDGLITHGEK YNKVVDAWSK ATEEIAKEMM KEISAVRKAP DGSEQQVNSI
730 740 750 760 770 780
YMMAHSGARG SPAQMRQLAG MRGLMAKPSG EIIETPIISN FKEGLSVLEY FNSTHGARKG
790 800 810 820 830 840
LADTALKTAN SGYLTRRLVD VAQDCIITQA DCGTSLGIKM RAIVDAGTVV ASLGSRILGR
850 860 870 880 890 900
TAGEDVRDPA TNEIIVKRGD LMEERDVEAI HQAGVQEVKI RSALTCELVN GICGKCYGRD
910 920 930 940 950 960
LARGTPVNHG EAVGVIAAQS IGEPGTQLTM RTFHIGGAAQ INEQSVIESN FDGKIVIKNR
970 980 990 1000 1010 1020
AIARNGEGHN VAMVRNMVIA IVDPDGTERA THRIQYGARV HVDEGDMVKR GQRIAEWDPY
1030 1040 1050 1060 1070 1080
TRPILTEVEG EIGFEDLIED QSISETLDES TGIAKRIVID WRSTRGGADL RPAIVIKGKD
1090 1100 1110 1120 1130 1140
GKVLKLARGG DARYMLSVDA ILSVDVGAQV KPGDILARIS TESAKTRDIT GGLPRVAELF
1150 1160 1170 1180 1190 1200
EARRPKDAAI IAEIAGTIRF GRDYKNKRRL SIEPLDKNEE AREYLIPKGK HIHLQDGDVV
1210 1220 1230 1240 1250 1260
EKGDFIVEGN PAPHDILAIK GIEELAAYLV NEIQEVYRLQ GVLINDKHIE VIVRQMLQKI
1270 1280 1290 1300 1310 1320
EITDQGDTDM ISGEQVDKIE FNALNAKAVE EGKKPATGNP VLLGITKASL QTRSFFSAAS
1330 1340 1350 1360 1370 1380
FQETTRVLTE AAVNGKVDPL EGLKENVIVG RLIPAGTGAS MAKIREVAVK RDRLILDERE
1390 1400
KQAAIVPAAA PEAEPLSLPP AE