Q6MK43

PR
Gene name
selU
Protein name
tRNA 2-selenouridine synthase
Names
Species
Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)
KEGG Pathway
bba:Bd2570
EC number
2.9.1.3: Selenotransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-81 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6MK43

Entry ID Method Resolution Chain Position Source
AF-Q6MK43-F1 Predicted AlphaFoldDB

No variants for Q6MK43

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6MK43

No associated diseases with Q6MK43

3 regional properties for Q6MK43

Type Name Position InterPro Accession
domain Transcription factor IIIC, 90kDa subunit, N-terminal 64 - 254 IPR024761
domain Transcription factor IIIC, putative zinc-finger 739 - 790 IPR024764
domain Domain of unknown function DUF5921 265 - 720 IPR045803

Functions

Description
EC Number 2.9.1.3 Selenotransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
transferase activity, transferring alkyl or aryl (other than methyl) groups Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
tRNA 2-selenouridine synthase activity Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA).

1 GO annotations of biological process

Name Definition
tRNA wobble uridine modification The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLKNIKPDQ LKNLFQQNIP LMDVRAPVEF SQGSIPGAVN LPVMNDDERA QVGTVYKNQG
70 80 90 100 110 120
NEAAVKLGHE LVSGLVKEQR VAAWKSFVQA HPEAVFYCFR GGQRSRISQA WLKEAGVERP
130 140 150 160 170 180
LLVGGFKAAR NYLIKQIEEF SVRQELISVS GPTGSGKTHF LRGLKGCPVI DLEALARHRG
190 200 210 220 230 240
SAFGNWEVPQ PTQVDYENNL AREILLLEDK IHGKIKPLVE DESRLIGRIS QPATFFIRLR
250 260 270 280 290 300
SSPVIWIDEP LPVRVDNVFD DYILNSSIGK SLEAAPRCAE ENDILRAQAL QLFARYRQSL
310 320 330 340 350 360
LAIQRKLGGL RAQEVMADLE KAELAYLNHA ELSGNKVWIE KLLQYYYDPM YLGSLERRHV
370
TVLFKGTRFE AEKFVHSLT