Q6M1A3
Gene name |
truD1 (MMP0014) |
Protein name |
Probable tRNA pseudouridine synthase D 1 |
Names |
tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D 1, tRNA-uridine isomerase D 1 |
Species |
Methanococcus maripaludis (strain S2 / LL) |
KEGG Pathway |
mmp:MMP0014 |
EC number |
5.4.99.27: Transferring other groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6M1A3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6M1A3-F1 | Predicted | AlphaFoldDB |
No variants for Q6M1A3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6M1A3 | |||||
No associated diseases with Q6M1A3
3 regional properties for Q6M1A3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translation elongation factor EFTs/EF1B, dimerisation | 71 - 275 | IPR014039 |
| conserved_site | Translation elongation factor Ts, conserved site | 12 - 27 | IPR018101-1 |
| conserved_site | Translation elongation factor Ts, conserved site | 75 - 85 | IPR018101-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.99.27 | Transferring other groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| tRNA pseudouridine synthase activity | Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| pseudouridine synthesis | The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs. |
| tRNA processing | The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFRQKHEDF | IVNEILEYEL | NDYGNYFLYK | LQKNGIENLK | AISYLSKNFE | VPTKEIGYCG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKDRHAITTQ | YVSIPKEYGK | LSLDEDNLKL | EYVGTIEKPL | KIGRLYGNRF | EIIARAVDKD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EFLKIADNIR | NLSSGAPNYY | DDQRFGSVFN | GKFIAKEILK | GNYEEVVKIL | LTSYTKSEKK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QLKDLKRFIA | KNWGNWDECL | EYIDKKQIRS | KMFRNMVKSL | TYENDFKKAF | KYVDNRLKEL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FISAYQSYLW | NECLKEFLKE | VIPKENRIYV | DYSCGTFLFY | ENIEEELFDK | LKEMDFPTIV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SDVEYTDPEK | RIIKAILKKE | RIKISDFEKL | DFGKLKYTKR | PIISIPEDVN | TGKFKSDELN |
| 370 | 380 | ||||
| SKKYKIDLEF | SLKKGSYATI | ILKRVFNIL |