Q6L126
Gene name |
radA |
Protein name |
DNA repair and recombination protein RadA |
Names |
|
Species |
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) |
KEGG Pathway |
pto:PTO0741 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6L126
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6L126-F1 | Predicted | AlphaFoldDB |
No variants for Q6L126
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6L126 | |||||
No associated diseases with Q6L126
6 regional properties for Q6L126
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Helix-hairpin-helix DNA-binding motif, class 1 | 11 - 30 | IPR003583-1 |
| domain | Helix-hairpin-helix DNA-binding motif, class 1 | 44 - 63 | IPR003583-2 |
| domain | AAA+ ATPase domain | 106 - 290 | IPR003593 |
| domain | DNA recombination and repair protein Rad51-like, C-terminal | 73 - 320 | IPR013632 |
| domain | DNA recombination and repair protein RecA, monomer-monomer interface | 261 - 323 | IPR020587 |
| domain | DNA recombination and repair protein RecA-like, ATP-binding domain | 85 - 256 | IPR020588 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent DNA damage sensor activity | A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis. |
| damaged DNA binding | Binding to damaged DNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA recombination | Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. |
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKNDKEKRE | LTIEDLPGVG | DATAEKLRES | GYDDIMTIAV | ASPKDLAEIS | GIAEGAAIKI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| INAARKYADV | GNFETGEEIL | NKRKEIKKLT | TGSSNLDNLL | GGGLETQSIT | EFFGEFGSGK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TQIMHQLAVN | ATMPVEKNGF | DSDVLIIDTE | NTFRPERIIQ | MARAKDLDPD | QTLERIHVAR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AYNSHHQILL | AEKAADMARE | YKIRLLIVDS | LTSHFRSEYV | GRGSLAERQQ | LLNRHMHDLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KFGTIYNAVI | AVTNQVSANP | AVFFGDPMNP | IGGNIVGHTA | TFRIYLRKAK | AGKRIARLID |
| 310 | 320 | ||||
| SPYLPEGETV | ITITESGITD | GEK |