Q6L0M1

PR
Gene name
PTO0896
Protein name
Digeranylgeranylglycerophospholipid reductase
Names
DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR
Species
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
KEGG Pathway
pto:PTO0896
EC number
1.3.1.101: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6L0M1

Entry ID Method Resolution Chain Position Source
AF-Q6L0M1-F1 Predicted AlphaFoldDB

No variants for Q6L0M1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6L0M1

No associated diseases with Q6L0M1

1 regional properties for Q6L0M1

Type Name Position InterPro Accession
domain FAD-binding domain 5 - 301 IPR002938

Functions

Description
EC Number 1.3.1.101 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

5 GO annotations of molecular function

Name Definition
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
geranylgeranyl reductase activity Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.

3 GO annotations of biological process

Name Definition
glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
membrane lipid biosynthetic process The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEVNYDVLVI GAGPAGSSAA RFAARKGLKT LLIEKRPDIG SPVRCGEGVS KSWMPEVELK
70 80 90 100 110 120
PEDHWISDEV KGARIYGPSE KKPIMLTAEN AGNEVGYVVE RDKFDKHIAA LAASEGADVW
130 140 150 160 170 180
VKSPALSVIK DGNRIVGAKV RHNSEIVDVR AKMVIAADGF ESEFGRWAGL KSLILAKNDI
190 200 210 220 230 240
ISCVEYRMIN VDSDEDYTDF YLGSCAPAGY IWVFPKGKHE ANVGIGVTIS KMRDRFDVKN
250 260 270 280 290 300
YLDAFIKSHP GYSKGKTIQL ITGGVSVSKV RDKFTLPGLL TVGDAARLID PITGGGIANG
310 320 330 340 350 360
MISGKYAAEV SKKAIDNEDY SQEMMNNYER MVKDKFERKH LRNWFAKEKL GTLSDETLDK
370 380 390
LVDVIADVKI NEISVEEILK AVQLKYPELV EELESLI