Q6KZ38
Gene name |
PTO1429 |
Protein name |
Bifunctional methyltransferase/endonuclease |
Names |
|
Species |
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) |
KEGG Pathway |
pto:PTO1429 |
EC number |
3.1.21.7: Endodeoxyribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6KZ38
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6KZ38-F1 | Predicted | AlphaFoldDB |
No variants for Q6KZ38
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6KZ38 | |||||
No associated diseases with Q6KZ38
1 regional properties for Q6KZ38
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding | 10 - 85 | IPR014048 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.21.7 | Endodeoxyribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| deoxyribonuclease V activity | Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate. |
| metal ion binding | Binding to a metal ion. |
| methyltransferase activity | Catalysis of the transfer of a methyl group to an acceptor molecule. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| methylation | The process in which a methyl group is covalently attached to a molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQSIDLYSYL | YSLLGQIPEG | MVTTYGDLAV | ALGDVKAARA | CGYMLSRNND | TENIPCYKVI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MSDGSLGGYS | LGIDEKIRRL | RNDGIEINNG | RIDLKRYRFN | NFDSSYPLKR | LQEEQEKIAG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LAVYSDDYNE | DKICAIDVSY | KDEIGYSVMV | SFENNEYDFK | TFIKETRFPY | IPGYLAYREF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PYIKELGKNF | DGTMIIDANG | LLHPRRCGLA | TYVGVIMNKP | SIGVAKSLLT | GSIKNGYVYY |
| 250 | 260 | 270 | 280 | 290 | |
| NNMPLGYMIN | SRTIVSPGNR | ISLESSINFI | RNLGKDHYPE | ILKIAHDRTV | ALRRNNII |