Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6IR75
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6IR75-F1 | Predicted | AlphaFoldDB |
No variants for Q6IR75
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6IR75 | |||||
No associated diseases with Q6IR75
5 regional properties for Q6IR75
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 150 - 158 | IPR000629 |
| domain | Helicase, C-terminal | 215 - 375 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 27 - 192 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 22 - 219 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 3 - 31 | IPR014014 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| COP9 signalosome | A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| DMEDDFMCDD | EEDYDLEYSE | DSNSEPNVDL | ENQYYNSKAL | KEDDPKAALS | SFQKVLELEG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKGEWGFKAL | KQMIKINFKL | GNYPEMMNRY | KQLLTYIRSA | VTRNYSEKSI | NSILDYISTS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KQMDLLQEFY | ETTLDALKDA | KNDRLWFKTN | TKLGKLYLER | EEYGKLQKIL | RQLHQSCQTD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DGEDDLKKGT | QLLEIYALEI | QMYTAQKNNK | KLKALYEQSL | HIKSAIPHPL | IMGVIRECGG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KMHLREGEFE | KAHTDFFEAF | KNYDESGSPR | RTTCLKYLVL | ANMLMKSGIN | PFDSQEAKPY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KNDPEILAMT | NLVSAYQNND | ITEFEKILKT | NHSNIMDDPF | IREHIEELLR | NIRTQVLIKL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IKPYTRIHIP | FISKELNIDV | ADVESLLVQC | ILDNTIHGRI | DQVNQLLELD | HQKRGGARYT |
| 430 | 440 | ||||
| ALDKWTNQLN | SLNQAVVSKL | A |