Q6IR61

PR
Gene name
nit2a
Protein name
Omega-amidase NIT2-A
Names
Nitrilase homolog 2
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
EC number
3.5.1.3: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

232-276 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6IR61

Entry ID Method Resolution Chain Position Source
AF-Q6IR61-F1 Predicted AlphaFoldDB

No variants for Q6IR61

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6IR61

No associated diseases with Q6IR61

2 regional properties for Q6IR61

Type Name Position InterPro Accession
domain Carbon-nitrogen hydrolase 4 - 255 IPR003010
domain Nit1/2, carbon-nitrogen hydrolase domain 5 - 260 IPR045254

Functions

Description
EC Number 3.5.1.3 In linear amides
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
2-oxoglutaramate amidase activity Catalysis of the reaction: 2-oxoglutaramate + H(2)O = 2-oxoglutarate + NH(3).
omega-amidase activity Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.

1 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKFKLSLVQ FLVSPVKSDN LNRACKLIKE AAQKGAQIVA LPECFNSPYG TTYFPEYAEK
70 80 90 100 110 120
IPGESTELLS QVAKECGIYL IGGSIPEEDC GKLYNTCAVF GPDGTLLVKH RKIHLFDIDV
130 140 150 160 170 180
PGKIRFQESE TLSPGDSFSV FDTPYCKVGV GICYDIRFAE LAQIYANKGC QLLVYPGAFN
190 200 210 220 230 240
MTTGPAHWEL LQRARALDNQ VYVATASPAR DEKASYVAWG HSTIVSPWGE VVAKAGSEET
250 260 270
VLSAEIDLQY LAEIREQIPI RRQRRRDLYN VEEKRN