Q6IP71

PR
Gene name
ralb-b
Protein name
Ras-related protein ralB-B
Names
XRalB-B
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:432329
EC number
3.6.5.2: Acting on GTP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

146-206 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6IP71

Entry ID Method Resolution Chain Position Source
AF-Q6IP71-F1 Predicted AlphaFoldDB

No variants for Q6IP71

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6IP71

No associated diseases with Q6IP71

1 regional properties for Q6IP71

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 16 - 169 IPR005225

Functions

Description
EC Number 3.6.5.2 Acting on GTP; involved in cellular and subcellular movement
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
  • Midbody
  • During late cytokinesis, enriched at the midbody
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
midbody A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
G protein activity A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).
GTP binding Binding to GTP, guanosine triphosphate.

5 GO annotations of biological process

Name Definition
actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
fibroblast growth factor receptor signaling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
Ras protein signal transduction The series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
regulation of developmental pigmentation Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
small GTPase mediated signal transduction The series of molecular signals in which a small monomeric GTPase relays a signal.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAANKNKNQS SLVLHKVIMV GSGGVGKSAL TLQFMYDEFV EDYEPTKADS YRKKVVLDGE
70 80 90 100 110 120
EVQIDILDTA GQEDYAAIRD NYFRSGEGFL LVFSITEHES FTATAEFREQ ILRVKAEEDK
130 140 150 160 170 180
IPLLVVGNKS DLEDRRQVPM DEARGKAEEW GVQYVETSAK TRANVDKVFF DLMREVRTKK
190 200
MSENKDKNGK KSGKSKKGFK QRCCLL