Q6GQV0
Gene name |
Tedc2 |
Protein name |
Tubulin epsilon and delta complex protein 2 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:72016 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6GQV0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6GQV0-F1 | Predicted | AlphaFoldDB |
40 variants for Q6GQV0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389387697 | 14 | C>Y | No | EVA | |
| rs3389387683 | 33 | Q>H | No | EVA | |
| rs252640581 | 62 | T>I | No | EVA | |
| rs3389399289 | 71 | C>S | No | EVA | |
| rs3389441776 | 71 | C>Y | No | EVA | |
| rs3389440189 | 98 | V>M | No | EVA | |
| rs3389437841 | 121 | A>T | No | EVA | |
| rs249218052 | 122 | A>S | No | EVA | |
| rs3389433242 | 146 | R>W | No | EVA | |
| rs224550702 | 147 | A>T | No | EVA | |
| rs108480734 | 151 | P>A | No | EVA | |
| rs3389387694 | 154 | Y>F | No | EVA | |
| rs243420067 | 196 | E>D | No | EVA | |
| rs108024045 | 199 | A>T | No | EVA | |
| rs3389436832 | 230 | A>T | No | EVA | |
| rs3389441769 | 242 | A>T | No | EVA | |
| rs247224776 | 242 | A>V | No | EVA | |
| rs3389418110 | 248 | H>N | No | EVA | |
| rs227344822 | 253 | A>V | No | EVA | |
| rs49700584 | 268 | A>V | No | EVA | |
| rs46464870 | 271 | R>Q | No | EVA | |
| rs3389430751 | 282 | L>P | No | EVA | |
| rs3407486310 | 290 | I>L | No | EVA | |
| rs45799807 | 290 | I>T | No | EVA | |
| rs3389399336 | 304 | T>S | No | EVA | |
| rs3407840981 | 325 | A>G | No | EVA | |
| rs3389399252 | 346 | C>S | No | EVA | |
| rs3407505175 | 370 | L>* | No | EVA | |
| rs3389436762 | 375 | L>F | No | EVA | |
| rs3407440522 | 379 | L>M | No | EVA | |
| rs33247125 | 415 | A>T | No | EVA | |
| rs3407547972 | 422 | G>E | No | EVA | |
| rs3407505100 | 424 | E>D | No | EVA | |
| rs3407505174 | 424 | E>V | No | EVA | |
| rs3407547976 | 426 | F>L | No | EVA | |
| rs3389407130 | 430 | L>H | No | EVA | |
| rs3389449750 | 435 | A>T | No | EVA | |
| rs3406509904 | 436 | D>E | No | EVA | |
| rs3405708088 | 436 | D>Y | No | EVA | |
| rs3407840970 | 437 | D>S | No | EVA |
No associated diseases with Q6GQV0
No regional properties for Q6GQV0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6GQV0 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| centriole | A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle. |
| cilium | A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of smoothened signaling pathway | Any process that activates or increases the frequency, rate or extent of smoothened signaling. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLGVKGNYLL | PADCAHRLVA | ELQGALDSCA | DRQRQLERSL | RVSRRLLQVW | EPARTPSPVP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ETKEEDPSPA | CAPSSQDLEE | LELLTQALEK | AVRVRKGVSN | AGQRDRTPTL | TSKAATSGAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AASHPRAPSR | GGSRVLGTRS | TKGIQRATAP | PKDYPEHRLR | SKGDKTHVRT | QDQTTGYGPD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRDQQMTPSS | AHHTTELFAL | KEKGTLLQLP | EDFRKAVSRN | SCLWAQLNSA | RTNDSTDATR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAKTQFLHKL | QMASGCSSHR | PSATEVEAHA | RILRKACMLL | RLRMQKELAI | APTDWMQEYR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CLLTLEGLQT | VVGQCLHRIQ | VLQAAVTEQL | PGECLAETRT | QASSVCGGEV | DSACSPELLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YASTEELQTL | ATLKLQVALL | HQQIHLEKVL | MAELLPLINT | QDPGGPPWLA | LCRAAYSLLC |
| 430 | |||||
| EGGERFLTVL | RDDPAD |