Q6GNL1
Gene name |
c1galt1 |
Protein name |
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
Names |
Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, Core 1 beta1,3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1 |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:444326 |
EC number |
2.4.1.122: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6GNL1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6GNL1-F1 | Predicted | AlphaFoldDB |
No variants for Q6GNL1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6GNL1 | |||||
No associated diseases with Q6GNL1
No regional properties for Q6GNL1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6GNL1 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.122 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan. |
| metal ion binding | Binding to a metal ion. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| angiogenesis | Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. |
| kidney development | The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. |
| O-glycan processing | The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSIICAKVAW | LPLTLGTAMG | FLITFYLART | LLERNSQPPL | ALRSWNNMEL | LPEVGMSHFH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LPEDNSVSEE | LSKKVRVLCW | IMTGPTNLKT | KAIHVKNSWT | RHCNVALFMS | SITDEDFPAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GLGTGEGRDK | LYWKTIRAFH | YAHKYYLNET | EWFFKADDDT | YVIMDNLRWM | LSNYTADQPI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YFGKRFKPYI | KQGYMSGGAG | YVLSREALIR | FVEGFRTGVC | KHTTSTEDVA | IGNCMQLMGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IAGDSRDTEK | RETFHPFPPE | HHLTMKFSES | KSFWYWSYCV | YPIVEGPQCC | SDLAISFHYI |
| 310 | 320 | 330 | 340 | 350 | |
| SPEDMYTLEY | FIYHLRAHGY | QYRYQPPLSD | NADNLPVYIE | NETVKPNRTI | SDFLEPPMES |