Q6GMY9

PR
Gene name
cse1l (xpo2)
Protein name
Exportin-2
Names
Exp2, Chromosome segregation 1-like protein, Importin-alpha re-exporter
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:444464
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6GMY9

Entry ID Method Resolution Chain Position Source
AF-Q6GMY9-F1 Predicted AlphaFoldDB

No variants for Q6GMY9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6GMY9

No associated diseases with Q6GMY9

3 regional properties for Q6GMY9

Type Name Position InterPro Accession
domain Importin-beta, N-terminal domain 29 - 102 IPR001494
domain Exportin-2, C-terminal 527 - 962 IPR005043
domain Exportin-2, central domain 156 - 525 IPR013713

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Shuttles between the nucleus and the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
small GTPase binding Binding to a small monomeric GTPase.

1 GO annotations of biological process

Name Definition
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELSEGNLQG LTEYLKKTLD PDPAVRRPAE KYLESVEGNQ NYPLLLLTLV ERSQDNVIKV
70 80 90 100 110 120
CSAVTFKNYI KRNWRIVEDE SNKICEADRI AVKSSIINLM LRSPEQIQKQ LSDAISIIGR
130 140 150 160 170 180
EDFPQKWPNL LTEMVNRFQS GDFHVINGVL HTAHSLFKRY RHEFKSSELW TEIKLVLDTF
190 200 210 220 230 240
AGPLTDLFKA TIELCNTHAN DVGALKVLFS SLNLIAKLFH SLNFQDLPEF FEDNMETWMT
250 260 270 280 290 300
NFHNLLTLDN KLLQTDDEEE AGLLELLKSQ ICDNAALYAQ KYDEEFQPYL PRFVTAIWNL
310 320 330 340 350 360
LVTTGQEVKY DLLVSNAIQF LASVCERPHY KNLFEDPSTL TSICEKVIVP NMEFRAADEE
370 380 390 400 410 420
AFEDNSEEYI RRDLEGSDID TRRRAACDLV RGLCKFFEGP VTNIFSGYVN SMLQEYAKNP
430 440 450 460 470 480
SVNWKHKDAA IYLVTSLASK AQTQKHGITQ ANELVNLTEF FVNHILPDLK SANINQYPVL
490 500 510 520 530 540
KADGIKYIMF FRSQIPREQL LVTIPLLIAY LQAESIVVHT YAAHALERFF TMKGAATTTL
550 560 570 580 590 600
IVAADMMPYV ELLLANLFKA LSLPGSTENE YIMKAIMRSF SLLQEAIIPY IPSVISQLTQ
610 620 630 640 650 660
KLLAVSKNPS KPHFNHYMFE AICLSIRITC RANPAAVASF EDALFLVFTE ILQSDVQEFI
670 680 690 700 710 720
PYVFQVMSLL LEIHTTDIPP SYMALFPHLL QPVLWERTGN IPPLVRLLQA YLERGATTIA
730 740 750 760 770 780
ASASDKIPGL LGVFQKLIAS KANDHQGFYL LNSIIEHLPA ECIEQYKRQI FIVLFQRLQS
790 800 810 820 830 840
SKTTKFVKSF LVFLNLFCIK FGAIALQEMF DSIQPKMFGM VVEKIIIPEI QKVSGPIEKK
850 860 870 880 890 900
ICAVGLTKVL TECPVMMDTE YTKLWTPLLQ ALIGLFELPE DDTIPDDEHF IDIEDTPGYQ
910 920 930 940 950 960
AAFSQLAFAG KKEHDPIGEM VNNPKILLAQ SLHKLSTACP GRVPSMISTS LNAEALQFLQ
970
GYLQAGSVSL V