Q6GIX4

PR
Gene name
copB (SAR0720)
Protein name
Probable copper-transporting P-type ATPase B
Names
Species
Staphylococcus aureus (strain MRSA252)
KEGG Pathway
sar:SAR0720
EC number
7.2.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-66 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6GIX4

Entry ID Method Resolution Chain Position Source
AF-Q6GIX4-F1 Predicted AlphaFoldDB

No variants for Q6GIX4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6GIX4

No associated diseases with Q6GIX4

2 regional properties for Q6GIX4

Type Name Position InterPro Accession
ptm P-type ATPase, phosphorylation site 374 - 380 IPR018303
domain P-type ATPase, haloacid dehalogenase domain 354 - 621 IPR044492

Functions

Description
EC Number 7.2.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
P-type monovalent copper transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNNKKHQNH EHHSHQEHEN HTSHGNHEHH HHGNFKSKFF ISLIFAIPII ILSPMMGVKL
70 80 90 100 110 120
PFQISFTGSD WIVLILATIL FFYGGKPFLS GAKDEISTKK PGMMTLVALG ISVAYIYSLY
130 140 150 160 170 180
AFYMNNFSGS STHTMDFFWE LATLILIMLL GHWIEMNAVG NAGNALKKMA ELLPNTAVKL
190 200 210 220 230 240
IDNNQREEVK ISDIHIDDIV EVRAGESIPT DGIIVRGETS IDESLVTGES KKVHKTHNDD
250 260 270 280 290 300
VIGGSINGSG TVQVKVTATG ENGYLSQVMG LVNQAQNDKS KAELLSDKVA GYLFYFAVSI
310 320 330 340 350 360
GLISFIVWML IQNNVDFALE RLVTVLVIAC PHALGLAIPL VTARSTSIGA HNGLIIKNRE
370 380 390 400 410 420
SVEIAQHIDY IMMDKTGTLT EGNFSVNHYE SFTDELNNEE ILSLFASLES NSNHPLATGI
430 440 450 460 470 480
VDFAKGKNIS YATPQEVNNI PGVGLEGTVD NKKLKIVNVS YLDKSNFDYN KEQFTNLAQQ
490 500 510 520 530 540
GNSISYLIHD RQVIGIIAQG DKIKESSKQM VSDLLSRNIT PVMLTGDNKE VAQTVAEELG
550 560 570 580 590 600
ISDVHAQLMP EDKESIIQDY QSNGSKIMMV GDGINDAPSL IRADIGMAIG AGTDVAIESG
610 620 630 640 650 660
DVILVKSNPS DIINFLSLSK NTMKKMVQNL WWGAGYNVIA VPLAAGILAS IGLILSPAVG
670 680
AILMSLSTII VAINAFTLKL K