Q6GDP8
Gene name |
feoB (SAR2630) |
Protein name |
Fe(2+) transporter FeoB |
Names |
Ferrous iron transport protein B |
Species |
Staphylococcus aureus (strain MRSA252) |
KEGG Pathway |
sar:SAR2630 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6GDP8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6GDP8-F1 | Predicted | AlphaFoldDB |
No variants for Q6GDP8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6GDP8 | |||||
No associated diseases with Q6GDP8
5 regional properties for Q6GDP8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ferrous iron transport protein B, C-terminal | 454 - 506 | IPR011640 |
| domain | Nucleoside transporter/FeoB GTPase, Gate domain | 350 - 444 | IPR011642-1 |
| domain | Nucleoside transporter/FeoB GTPase, Gate domain | 511 - 635 | IPR011642-2 |
| domain | FeoB-type guanine nucleotide-binding (G) domain | 1 - 161 | IPR030389 |
| domain | FeoB, cytosolic helical domain | 170 - 259 | IPR041069 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ferrous iron transmembrane transporter activity | Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. |
| GTP binding | Binding to GTP, guanosine triphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| iron ion homeostasis | Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MENYCILGNP | NVGKTSLFNA | LTGSYEYIGN | WSGVTVEKKV | GKLKENVGQL | IDLPGTYDLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PISKDETVVT | DYLLNDSFSG | IINIVDASQL | KRNMQLTVQL | LELNQPIYIG | LNMIDVATKR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GIKIDYHKLM | KKLKTPIFPV | VARTGKGTKH | LLGEIKHLGE | GYQPHFKINY | GEKIEETIKN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MCQIIMTETS | HDKYQARFIA | IQFLLNNMQI | ANELNSEVVN | KLSSLRDQVA | EQVEAVSVRR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EMERIRNHYI | ETLLQDVVTY | PDEDKQYFSS | RIDKILTHKY | IGMPIFLAIM | WLIFQTTFTW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IGTPLSDQLD | AFIGGTFTDS | VKTIMNYLGV | IPFLQDLITD | GIIAGVGSVL | VFVPQIVVLF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FFISLLEDSG | YMARIAVLMD | RIMESFGLSG | KSFIPMIIGF | GCNVPSIMAA | RSIENEKERL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TTILIAPFMS | CSARLPVYAL | FVGIFFKENQ | SLVVLSLYVL | GIIMAFLVST | VLTKTVLKND |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NAIFIVELPT | YRVPSIKTLW | RSTWEKAKGF | VRKAGTFIFG | GSVVIWLLSY | VGPHGINVNI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NQSFLHMVGS | FFGMLVQPLG | FGTWQAGATL | VPGFLAKEVI | VSSMAIIYSS | GDAGLVNVIQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NQFTPLSAYA | FMIFILLYIP | CVSTVAAIRK | ETYSWKWTAL | AVAYPLVTAY | VLTFIFYQVG |
| HLFV |