Q6G9M1
Gene name |
guaC |
Protein name |
GMP reductase |
Names |
Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase |
Species |
Staphylococcus aureus (strain MSSA476) |
KEGG Pathway |
sas:SAS1277 |
EC number |
1.7.1.7: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6G9M1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6G9M1-F1 | Predicted | AlphaFoldDB |
No variants for Q6G9M1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6G9M1 | |||||
No associated diseases with Q6G9M1
6 regional properties for Q6G9M1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA gyrase B subunit, C-terminal | 573 - 633 | IPR002288 |
| domain | Histidine kinase/HSP90-like ATPase | 39 - 183 | IPR003594 |
| domain | TOPRIM domain | 428 - 542 | IPR006171 |
| domain | DNA topoisomerase, type IIA, subunit B, domain 2 | 231 - 400 | IPR013506 |
| conserved_site | DNA topoisomerase, type IIA, conserved site | 432 - 440 | IPR018522 |
| domain | DNA gyrase subunit B, TOPRIM domain | 428 - 541 | IPR034160 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.7.1.7 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| GMP reductase complex | An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+). |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| GMP reductase activity | Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| purine nucleotide metabolic process | The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKIFDYEDIQ | LIPNKCIVES | RSECDTTIQF | GPKKFKLPVV | PANMQTVMNE | KLAKWFAEND |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YFYIMHRFDE | EARIPFIKHM | QNSGLFASIS | VGVKKAEFDF | IEKLAQEKLI | PEYITIDIAH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GHSDSVINMI | KHIKNHIPDS | FVIAGNVGTP | EGVRELENAG | ADATKVGIGP | GRVCITKIKT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GFGTGGWQLA | ALNICSKAAR | KPLIADGGIR | THGDIAKSIR | FGASMVMIGS | LFAAHEESPG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ETVELDGKQY | KEYFGSASEF | QKGEHKNVEG | KKMFVEHKGS | LMDTLKEMQQ | DLQSSISYAG |
| 310 | 320 | ||||
| GKDLKSLRTV | DYVIVRNSIF | NGDRD |