Q6G327

PR
Gene name
ppk
Protein name
Polyphosphate kinase
Names
ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase
Species
Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) (Rochalimaea henselae)
KEGG Pathway
bhe:BH09820
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

660-726 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6G327

Entry ID Method Resolution Chain Position Source
AF-Q6G327-F1 Predicted AlphaFoldDB

No variants for Q6G327

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6G327

No associated diseases with Q6G327

4 regional properties for Q6G327

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 136 - 331 IPR024953
domain Polyphosphate kinase N-terminal domain 22 - 127 IPR025198
domain Polyphosphate kinase C-terminal domain 2 514 - 690 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 341 - 504 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKTVADQIS LSDITMKNPA RFINREFSWL QFNNRVLMEA ANSKNPLLER LQFLSISATN
70 80 90 100 110 120
LDEFFMVRVA GLAAQIRAGV TACSADGRTP QEQLDFVLAE ISCLQDNQLR ELSILRHELK
130 140 150 160 170 180
QNNIEIICSA GLSETEKSWI EKYFLDTIFP VLTPLSVDPV RPFPFIPNLG FSIALQLSRC
190 200 210 220 230 240
ADQHSFIALL PLPTTLRRFI PLPQKDNRFR FIACEDVINL FMRHVFPDYE VEGIGTFRVI
250 260 270 280 290 300
RDSDIEVEEE AEDLVHFFET ALKRRRRGQV IRIEFEAKMP DHLRQFITNG LAVPEYCINV
310 320 330 340 350 360
LDGFLALNTV SEIVSIPRND LKFAPYDPRV PECICQHKGD CFAAIRQNDI VIHHPYESFD
370 380 390 400 410 420
VVVEFLRQAA RDPDVIEIKQ TLYRTSNDSP IVSALIEAAE QGKSVTALVE LKARFDEEAN
430 440 450 460 470 480
IRWARDLERA GVQVFFGFIA LKTHAKMSLV VRREGKRRCS YVHLGTGNYH PINAKVYTDL
490 500 510 520 530 540
SFFTTDDDIA HDVALLFNYI AEYVRPNEAM KIAFSPLTLR SRILEHIEGE ITNARQGQLA
550 560 570 580 590 600
AIWMKVNALV DPEIIDALYR ASQAGVQIDL VVRGICCLRP GIPGISDNIR VKSIVGRFLE
610 620 630 640 650 660
HSRIFCFGNG VNLPSENALV YFGSADMMPR NLDYRIEILV PVFNKMVRQQ ILLQVMLANI
670 680 690 700 710 720
IDNQQSFDIL NDGTSQLITP QRGESPFNAQ EYFMANAGLS RMERSFDSSV SHLVALYQQK
VKLYKD