Q6FVE6

PR
Gene name
PFA4
Protein name
Palmitoyltransferase PFA4
Names
Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0E02497g
EC number
2.3.1.225: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

290-376 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FVE6

Entry ID Method Resolution Chain Position Source
AF-Q6FVE6-F1 Predicted AlphaFoldDB

No variants for Q6FVE6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FVE6

No associated diseases with Q6FVE6

1 regional properties for Q6FVE6

Type Name Position InterPro Accession
domain Palmitoyltransferase, DHHC domain 77 - 204 IPR001594

Functions

Description
EC Number 2.3.1.225 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
protein-cysteine S-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-

1 GO annotations of biological process

Name Definition
protein palmitoylation The covalent attachment of a palmitoyl group to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPVKLKWPWL GIAIPSFLIA SIGYCAHYFI LLNFLSLRKQ LWYQFCQTMI WLSYYLAIYT
70 80 90 100 110 120
PPGKPPTNFK PSKNEWKVYC KKCKCYKPER SHHCKTCNQC VLMMDHHCPW TMNCVGYNNF
130 140 150 160 170 180
PHFIRFLFWV IVGTTSLAIF LTTRIHSIWV HRSSPSYLYY KSELIFLTIL TPLNAFILLT
190 200 210 220 230 240
ISILMIRCLF NQIFNGRSQI ESWEMDRLET LARMSKLLPI LIENVWYIFP NLRNEHVESQ
250 260 270 280 290 300
AEALLNKKRL SLDELVNFPY DLGPFRNAIQ LLGTPPLWLY PFSGPQDDGL HFQKNEESMI
310 320 330 340 350 360
EDPNSLNDII LCLPWPPDST KHLNSTSEHT SNVQIISEEG EQVIRIRTPE KKLSRSEWLN
370
DWGESLEDFG VDVDVE