Q6FVB6

PR
Gene name
CHO2 (CAGL0E03201g)
Protein name
Phosphatidylethanolamine N-methyltransferase
Names
PE methyltransferase, PEAMT, PEMT
Species
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
KEGG Pathway
cgr:CAGL0E03201g
EC number
2.1.1.17: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6FVB6

Entry ID Method Resolution Chain Position Source
AF-Q6FVB6-F1 Predicted AlphaFoldDB

No variants for Q6FVB6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6FVB6

No associated diseases with Q6FVB6

No regional properties for Q6FVB6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6FVB6

Functions

Description
EC Number 2.1.1.17 Methyltransferases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
phosphatidylethanolamine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.

2 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
phosphatidylcholine biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVVANVEVK MKGRTRSSGI HFDPPETHDM VRSLFDPRIK KSYLEIVIAS VILSNFVVCY
70 80 90 100 110 120
WLLNSYGLQV AKYCFLGQYV FWRLSYNLGI GCVLHYQSHY ETLTNFAKTH RLFSKKNNAF
130 140 150 160 170 180
LAKFAQFEIS SKMPTNYNIS EYPEELNVWL LFRQFVDLIL MQDFATYMVY VYLSMSSWRF
190 200 210 220 230 240
TWRTGLGLAM ILFNIWVKLD AHRVVKDYAW YWGDFFFLQD SELIFDGVFN ISPHPMYSIG
250 260 270 280 290 300
YLGYYGLSLI CGDYRVLLVS VFGHLLQFVF LKYVETPHID RTYGTSETKE LTNGTVDDQI
310 320 330 340 350 360
AREHNDYTHP LISNGLFLEN FDKLRFTDYF TVFTTWAIFS WTVFGTPTSR RLFYLTFVAK
370 380 390 400 410 420
LSTWLLLSYV LYRQSKEKWF TKLYLKNGYT QVHCFQQWQF LYNYSLVISY TLLVCQTLIK
430 440 450 460 470 480
IKEIFPAIDY SQIIFGLICC ALQIWCNTEI RSAISDFGWF YGDFFLINYI VDRKLTTQGI
490 500 510 520 530 540
YRYLNNPEAI LGVAGVWGSV LMTDFAWENI ALGMLWTATN FVLVKFIETP HVSKVYGPSA
550 560 570 580 590 600
DRMSGVEKTL YNIKPLRRVS ELVDKAEHII LRSFLNHETP LSSNYLKSGS PISFSNNSDD
610 620 630 640 650 660
SDSGSEEAVP KPDRADKDIL WENAVEHAIH KVSSQLGPYC DLEILGLDEK NKAILPNVLT
670 680 690 700 710 720
VEWKLPTKLY HEKDWIGLYN VLDTKNIRER TRVSSSGHWS GTSPEGYPHD LKNTKCIQEF
730 740 750 760 770 780
QRTENYVCGK ISFDANLMYF KHGIYEFRYH SKGTHRVLLV SKPFEISYPH FEASSAEVLN
790 800 810 820 830 840
IELKKFLTEL HVLKNNRFDD KGNDYFKILN LKRLIRDSVG IELSTDYIKR VNGDIDVIAK
850
RVWEIKEVLD KLE