Q6FUJ7
Gene name |
SYF1 (CAGL0F02915g) |
Protein name |
Pre-mRNA-splicing factor SYF1 |
Names |
|
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0F02915g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FUJ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FUJ7-F1 | Predicted | AlphaFoldDB |
No variants for Q6FUJ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FUJ7 | |||||
No associated diseases with Q6FUJ7
9 regional properties for Q6FUJ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | HAT (Half-A-TPR) repeat | 46 - 77 | IPR003107-1 |
| repeat | HAT (Half-A-TPR) repeat | 313 - 348 | IPR003107-2 |
| repeat | HAT (Half-A-TPR) repeat | 458 - 494 | IPR003107-3 |
| repeat | HAT (Half-A-TPR) repeat | 496 - 551 | IPR003107-4 |
| repeat | HAT (Half-A-TPR) repeat | 589 - 623 | IPR003107-5 |
| repeat | HAT (Half-A-TPR) repeat | 628 - 664 | IPR003107-6 |
| repeat | HAT (Half-A-TPR) repeat | 707 - 741 | IPR003107-7 |
| repeat | HAT (Half-A-TPR) repeat | 743 - 777 | IPR003107-8 |
| repeat | Tetratricopeptide repeat | 445 - 472 | IPR019734 |
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| Prp19 complex | A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. |
| U2-type catalytic step 1 spliceosome | A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs. |
| U2-type catalytic step 2 spliceosome | A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs. |
| U2-type post-mRNA release spliceosomal complex | A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs. |
| U2-type prespliceosome | A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| generation of catalytic spliceosome for first transesterification step | Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MADIDQYILD | DSDIAFEYEL | QKSPSVEVWQ | RYIAHWEAQV | CEDGVRSARH | ILWLYERMVT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QFPTLTVWEQ | YIGWFRRQYK | LDQYLDTFKL | YERCINSVKG | PLGVFAVEVM | LFCISTFDLD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IIMKGLQLVL | HRCNKDEVER | IWNIVLGFAL | EHVLPSEEGP | NNIDFSAFND | RNYEDLRLDI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YKLLFLGGDQ | TEIEDDEEDE | DVDKWTASLL | RYYLQVANED | KYDETLRLLI | RTKDIKIIKE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CFDLYIFNDK | TGKNNRESKK | EYDFDLYIYY | LDTLDKLRLD | KDYKSVFDNL | LEKYPQHRVL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LTLKLADFHM | KRADFDKMEK | VLTKALSETV | KTNEFIAIYT | YHVNFEQAYV | ETIFDEMRDD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PEIQVQKKWK | SEMDDHLIIL | GDLTSRYHLL | VNDLKIRQNP | NSVSNWLERT | TLFEDFDKKC |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EVFVEAIKTI | DPIKVKDKEY | GMLGKLWCDY | AKVYWSNKSY | EEARTIYESA | TKVPFPDLQD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LEIVWHTWAV | NEFQIHNIER | ALKILRKALT | VPPSYESIID | RFKSENRRLP | SQTILFTSKR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LWNYYIDLLE | SIPTIDANDV | IRAYDTLMTL | KLITPVGILN | YATFLKQNNN | LHGSLQVYEK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GINMFPPEIC | YELWTLLLDE | VMEPAHQATK | ERIRELFEQC | LQQLGNTDIN | INSIYVKYSD |
| 670 | 680 | 690 | 700 | 710 | 720 |
| FEIHNKLFSR | AIDLLMSGAR | RPYTNKEQLK | QRVDLWESAI | SKCEEFLGPD | SLRQLLSECI |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QELPNSKAIT | YVLKFTKLEM | SLSDYTRARE | LLQYGAQLLP | PIKNEELWGL | WEQFELEHGD |
| 790 | 800 | 810 | 820 | 830 | |
| KSYYKEMLLL | KQKLEKEMKV | DTEEVSKGQG | NVQFVASSVK | NQEAKTNPDE | IEIDI |