Q6FSD2
Gene name |
CFT1 (CAGL0H01463g) |
Protein name |
Protein CFT1 |
Names |
Cleavage factor two protein 1 |
Species |
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) |
KEGG Pathway |
cgr:CAGL0H01463g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6FSD2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6FSD2-F1 | Predicted | AlphaFoldDB |
No variants for Q6FSD2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6FSD2 | |||||
No associated diseases with Q6FSD2
1 regional properties for Q6FSD2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cleavage/polyadenylation specificity factor, A subunit, C-terminal | 990 - 1320 | IPR004871 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mRNA cleavage and polyadenylation specificity factor complex | A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA polyadenylation | The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript. |
| pre-mRNA cleavage required for polyadenylation | The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation. |
| termination of RNA polymerase II transcription | A transcription termination process that completes the production of a primary RNA polymerase II transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNVYDDVIDP | TVVSHSVCGH | FTTTDYLELI | VIRTDVLSIY | KPIRSGRLYL | MEEHKLSGRI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NDVALIPKHS | NGSNGNGINL | SYLLLSTGVA | KLSLLMYNNM | TSSIETISLH | FYEDKFESAT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MLDLARNSQL | RIEPNGNYAM | LFNNDVLAIL | PFYTGINEDE | DEDYINNDKS | KINDNSKKSL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FKRKKGKTQN | NKVTHPSIII | NCSELGPQIK | NIKDIQFLCG | FTKSTIGVLY | QPQLAWCGNS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QLVPLPTNYA | IISLDMKFSI | DATTFDKAII | SEISQLPSDW | HTIAPTLSGS | LILGVNEIAF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LDNTGVLQSI | LTLNSYSDKV | LPKVRVIDKS | SHEVFFNTGS | KFALIPSNEN | ERSVENILLF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DENGCIFNVD | LKSEGRLLTQ | FNITKLPLGE | DVLSQKSNPS | SVSIIWADGR | LDTYTIFIGF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QSGDATMLKL | NHLHSAIEVE | EPTFMKDYVN | KQASAAYNNE | DDDDDDDDFN | LYSDEENDQV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NNKNDRTFGT | NESNEPFTAQ | ELMELRNIGP | INSMCVGKVS | SIEDNVKGLP | NPNKQEISIV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| CTSGYGDGSH | LNAILASVQP | RVEKALKFIS | ITKIWNLHIK | GKDKFLITTD | STQSQSNIYE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IDNNFSQHKQ | GRLRRDATTI | HIATIGDNKR | IVQVTTNHLY | LYDLTFRRFS | TIKFDYEVVH |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VSVMDPYVLI | TLSRGDIKVF | ELENRNKKKF | VKVPLPEILT | EMVITSGLIL | KSNMCNEFLS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| GIGKSTIEQL | LFTFVTADNQ | IIFFTKDHND | RIFQLNGIDQ | LQDSLYISTY | QLPDEIIPDP |
| 790 | 800 | 810 | 820 | 830 | 840 |
| SIKQIMINKL | GNNSKDEYLT | ILTFGGEIYQ | YKKSRSRHSR | FYRNVGRNDH | PITGAPDNAY |
| 850 | 860 | 870 | 880 | 890 | 900 |
| PKGVSGIERI | MHYIPNFDGY | SVIFVTGNTP | YIIMKEDDSL | PRIFPFGNIP | IVSMSRWGEG |
| 910 | 920 | 930 | 940 | 950 | 960 |
| SVICIDDIKN | ARIYSLNQDN | IYYGNKLPIR | KIKIGSMLQN | YKTLNSIVYH | ERTQLYLVSY |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| TKEISYEAKA | EDGSLLIGYK | PELPNAKAFK | SGVLLINPKS | WEVIDELDLP | DNSLVNDMKS |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| SFIQIDTRTK | RKREYIIVGI | GYATMEDVPP | TGEFHIYDIT | EVVPEPGKPN | TNFKLKEIFK |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| EDIRGIVSVV | NGISGRFLIS | QSQKIMVRDV | QQDNSVIPVA | FLDVPVFVTS | LKTFGNLIVI |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| GDAMQGIQFV | GFDAEPYRMI | TLGSSITKFE | VISVEFLVNN | GDIYFLVTDR | DSIMHVLKYA |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| PDQPNTLSGQ | RLVHCSSFNL | HSLNNCTMLL | PKNDEFPRDQ | RYSRSFQTIT | AQVDGSISKI |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| VPVKEETYRR | LYFIQQQIID | KEPQLAGLNP | RMERQDNKYY | HLGHSLRPML | DFNIIKRFKD |
| 1330 | 1340 | 1350 | 1360 | ||
| MSMNRRSHIV | QKLGKNSNLE | VWRDLIDLEF | SLRSLKPTDQ | N |